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Cell-specific regulation of gene expression using splicing-dependent frameshifting.
Ling JP, Bygrave AM, Santiago CP, Carmen-Orozco RP, Trinh VT, Yu M, Li Y, Liu Y, Bowden KD, Duncan LH, Han J, Taneja K, Dongmo R, Babola TA, Parker P, Jiang L, Leavey PJ, Smith JJ, Vistein R, Gimmen MY, Dubner B, Helmenstine E, Teodorescu P, Karantanos T, Ghiaur G, Kanold PO, Bergles D, Langmead B, Sun S, Nielsen KJ, Peachey N, Singh MS, Dalton WB, Rajaii F, Huganir RL, Blackshaw S. Ling JP, et al. Nat Commun. 2022 Oct 1;13(1):5773. doi: 10.1038/s41467-022-33523-2. Nat Commun. 2022. PMID: 36182931 Free PMC article.
ASCOT identifies key regulators of neuronal subtype-specific splicing.
Ling JP, Wilks C, Charles R, Leavey PJ, Ghosh D, Jiang L, Santiago CP, Pang B, Venkataraman A, Clark BS, Nellore A, Langmead B, Blackshaw S. Ling JP, et al. Nat Commun. 2020 Jan 9;11(1):137. doi: 10.1038/s41467-019-14020-5. Nat Commun. 2020. PMID: 31919425 Free PMC article.
recount3: summaries and queries for large-scale RNA-seq expression and splicing.
Wilks C, Zheng SC, Chen FY, Charles R, Solomon B, Ling JP, Imada EL, Zhang D, Joseph L, Leek JT, Jaffe AE, Nellore A, Collado-Torres L, Hansen KD, Langmead B. Wilks C, et al. Among authors: ling jp. Genome Biol. 2021 Nov 29;22(1):323. doi: 10.1186/s13059-021-02533-6. Genome Biol. 2021. PMID: 34844637 Free PMC article.
A fluid biomarker reveals loss of TDP-43 splicing repression in pre-symptomatic ALS.
Irwin KE, Jasin P, Braunstein KE, Sinha I, Bowden KD, Moghekar A, Oh ES, Raitcheva D, Bartlett D, Berry JD, Traynor B, Ling JP, Wong PC. Irwin KE, et al. Among authors: ling jp. bioRxiv [Preprint]. 2023 Jan 24:2023.01.23.525202. doi: 10.1101/2023.01.23.525202. bioRxiv. 2023. PMID: 36789434 Free PMC article. Updated. Preprint.
Elevated nuclear TDP-43 induces constitutive exon skipping.
Carmen-Orozco RP, Tsao W, Ye Y, Sinha IR, Chang K, Trinh V, Chung W, Bowden K, Troncoso JC, Blackshaw S, Hayes LR, Sun S, Wong PC, Ling JP. Carmen-Orozco RP, et al. Among authors: ling jp. bioRxiv [Preprint]. 2023 May 12:2023.05.11.540291. doi: 10.1101/2023.05.11.540291. bioRxiv. 2023. PMID: 37215013 Free PMC article. Preprint.
A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS-FTD.
Irwin KE, Jasin P, Braunstein KE, Sinha IR, Garret MA, Bowden KD, Chang K, Troncoso JC, Moghekar A, Oh ES, Raitcheva D, Bartlett D, Miller T, Berry JD, Traynor BJ, Ling JP, Wong PC. Irwin KE, et al. Among authors: ling jp. Nat Med. 2024 Feb;30(2):382-393. doi: 10.1038/s41591-023-02788-5. Epub 2024 Jan 26. Nat Med. 2024. PMID: 38278991 Free PMC article.
Author Correction: A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS-FTD.
Irwin KE, Jasin P, Braunstein KE, Sinha IR, Garret MA, Bowden KD, Chang K, Troncoso JC, Moghekar A, Oh ES, Raitcheva D, Bartlett D, Miller T, Berry JD, Traynor BJ, Ling JP, Wong PC. Irwin KE, et al. Among authors: ling jp. Nat Med. 2024 May;30(5):1504. doi: 10.1038/s41591-024-02966-z. Nat Med. 2024. PMID: 38580817 Free PMC article. No abstract available.
30 results