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DNA damage response and repair genes in advanced bone and soft tissue sarcomas: An 8-gene signature as a candidate predictive biomarker of response to trabectedin and olaparib combination.
Merlini A, Centomo ML, Ferrero G, Chiabotto G, Miglio U, Berrino E, Giordano G, Brusco S, Pisacane A, Maldi E, Sarotto I, Capozzi F, Lano C, Isella C, Crisafulli G, Aglietta M, Dei Tos AP, Sbaraglia M, Sangiolo D, D'Ambrosio L, Bardelli A, Pignochino Y, Grignani G. Merlini A, et al. Among authors: pignochino y. Front Oncol. 2022 Aug 30;12:844250. doi: 10.3389/fonc.2022.844250. eCollection 2022. Front Oncol. 2022. PMID: 36110934 Free PMC article.
Serial transplantations in nonobese diabetic/severe combined immunodeficiency mice of transduced human CD34+ cord blood cells: efficient oncoretroviral gene transfer and ex vivo expansion under serum-free conditions.
Gammaitoni L, Lucchi S, Bruno S, Tesio M, Gunetti M, Pignochino Y, Migliardi G, Lazzari L, Aglietta M, Rebulla P, Piacibello W. Gammaitoni L, et al. Among authors: pignochino y. Stem Cells. 2006 May;24(5):1201-12. doi: 10.1634/stemcells.2005-0408. Epub 2006 Jan 12. Stem Cells. 2006. PMID: 16410386
Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways.
Pignochino Y, Grignani G, Cavalloni G, Motta M, Tapparo M, Bruno S, Bottos A, Gammaitoni L, Migliardi G, Camussi G, Alberghini M, Torchio B, Ferrari S, Bussolino F, Fagioli F, Picci P, Aglietta M. Pignochino Y, et al. Mol Cancer. 2009 Dec 10;8:118. doi: 10.1186/1476-4598-8-118. Mol Cancer. 2009. PMID: 20003259 Free PMC article.
A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study.
Grignani G, Palmerini E, Dileo P, Asaftei SD, D'Ambrosio L, Pignochino Y, Mercuri M, Picci P, Fagioli F, Casali PG, Ferrari S, Aglietta M. Grignani G, et al. Among authors: pignochino y. Ann Oncol. 2012 Feb;23(2):508-16. doi: 10.1093/annonc/mdr151. Epub 2011 Apr 28. Ann Oncol. 2012. PMID: 21527590 Free article. Clinical Trial.
Ex vivo allogeneic stimulation significantly improves expansion of cytokine-induced killer cells without increasing their alloreactivity across HLA barriers.
Todorovic M, Mesiano G, Gammaitoni L, Leuci V, Giraudo Diego L, Cammarata C, Jordaney N, Carnevale-Schianca F, Gallo S, Fagioli F, Piacibello W, Elia AR, Pignochino Y, Dell'aglio C, Grignani G, Cignetti A, Aglietta M, Sangiolo D. Todorovic M, et al. Among authors: pignochino y. J Immunother. 2012 Sep;35(7):579-86. doi: 10.1097/CJI.0b013e31826b1fd9. J Immunother. 2012. PMID: 22892454
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