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DNA damage response and repair genes in advanced bone and soft tissue sarcomas: An 8-gene signature as a candidate predictive biomarker of response to trabectedin and olaparib combination.
Merlini A, Centomo ML, Ferrero G, Chiabotto G, Miglio U, Berrino E, Giordano G, Brusco S, Pisacane A, Maldi E, Sarotto I, Capozzi F, Lano C, Isella C, Crisafulli G, Aglietta M, Dei Tos AP, Sbaraglia M, Sangiolo D, D'Ambrosio L, Bardelli A, Pignochino Y, Grignani G. Merlini A, et al. Among authors: isella c. Front Oncol. 2022 Aug 30;12:844250. doi: 10.3389/fonc.2022.844250. eCollection 2022. Front Oncol. 2022. PMID: 36110934 Free PMC article.
A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.
Bertotti A, Migliardi G, Galimi F, Sassi F, Torti D, Isella C, Corà D, Di Nicolantonio F, Buscarino M, Petti C, Ribero D, Russolillo N, Muratore A, Massucco P, Pisacane A, Molinaro L, Valtorta E, Sartore-Bianchi A, Risio M, Capussotti L, Gambacorta M, Siena S, Medico E, Sapino A, Marsoni S, Comoglio PM, Bardelli A, Trusolino L. Bertotti A, et al. Among authors: isella c. Cancer Discov. 2011 Nov;1(6):508-23. doi: 10.1158/2159-8290.CD-11-0109. Epub 2011 Sep 2. Cancer Discov. 2011. PMID: 22586653 Free article.
TNF-α promotes invasive growth through the MET signaling pathway.
Bigatto V, De Bacco F, Casanova E, Reato G, Lanzetti L, Isella C, Sarotto I, Comoglio PM, Boccaccio C. Bigatto V, et al. Among authors: isella c. Mol Oncol. 2015 Feb;9(2):377-88. doi: 10.1016/j.molonc.2014.09.002. Epub 2014 Sep 26. Mol Oncol. 2015. PMID: 25306394 Free PMC article.
Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.
Picco G, Petti C, Sassi F, Grillone K, Migliardi G, Rossi T, Isella C, Di Nicolantonio F, Sarotto I, Sapino A, Bardelli A, Trusolino L, Bertotti A, Medico E. Picco G, et al. Among authors: isella c. J Natl Cancer Inst. 2016 Oct 22;109(2):djw209. doi: 10.1093/jnci/djw209. Print 2017 Feb. J Natl Cancer Inst. 2016. PMID: 27771609 Free article.
Rituximab Treatment Prevents Lymphoma Onset in Gastric Cancer Patient-Derived Xenografts.
Corso S, Cargnelutti M, Durando S, Menegon S, Apicella M, Migliore C, Capeloa T, Ughetto S, Isella C, Medico E, Bertotti A, Sassi F, Sarotto I, Casorzo L, Pisacane A, Mangioni M, Sottile A, Degiuli M, Fumagalli U, Sgroi G, Molfino S, De Manzoni G, Rosati R, De Simone M, Marrelli D, Saragoni L, Rausei S, Pallabazzer G, Roviello F, Cassoni P, Sapino A, Bass A, Giordano S. Corso S, et al. Among authors: isella c. Neoplasia. 2018 May;20(5):443-455. doi: 10.1016/j.neo.2018.02.003. Epub 2018 Mar 23. Neoplasia. 2018. PMID: 29574251 Free PMC article.
A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology.
Corti G, Bartolini A, Crisafulli G, Novara L, Rospo G, Montone M, Negrino C, Mussolin B, Buscarino M, Isella C, Barault L, Siravegna G, Siena S, Marsoni S, Di Nicolantonio F, Medico E, Bardelli A. Corti G, et al. Among authors: isella c. Clin Colorectal Cancer. 2019 Jun;18(2):91-101.e3. doi: 10.1016/j.clcc.2019.02.008. Epub 2019 Mar 7. Clin Colorectal Cancer. 2019. PMID: 30981604 Free article. Clinical Trial.
Evolving neoantigen profiles in colorectal cancers with DNA repair defects.
Rospo G, Lorenzato A, Amirouchene-Angelozzi N, Magrì A, Cancelliere C, Corti G, Negrino C, Amodio V, Montone M, Bartolini A, Barault L, Novara L, Isella C, Medico E, Bertotti A, Trusolino L, Germano G, Di Nicolantonio F, Bardelli A. Rospo G, et al. Among authors: isella c. Genome Med. 2019 Jun 28;11(1):42. doi: 10.1186/s13073-019-0654-6. Genome Med. 2019. PMID: 31253177 Free PMC article.
69 results