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De novo designed proteins neutralize lethal snake venom toxins.
Baker D, Torres SV, Valle MB, Mackessy S, Menzies S, Casewell N, Ahmadi S, Burlet N, Muratspahić E, Sappington I, Overath M, Rivera-de-Torre E, Ledergerber J, Laustsen AH, Boddum K, Bera A, Kang A, Brackenbrough E, Cardoso I, Crittenden E, Edge R, Decarreau J, Ragotte R, Pillai A, Abedi M, Han H, Gerben S, Murray A, Skotheim R, Stuart L, Stewart L, Fryer T, Jenkins T. Baker D, et al. Res Sq [Preprint]. 2024 May 17:rs.3.rs-4402792. doi: 10.21203/rs.3.rs-4402792/v1. Res Sq. 2024. PMID: 38798548 Free PMC article. Preprint.
Senescent Macrophages Release Inflammatory Cytokines and RNA-Loaded Extracellular Vesicles to Circumvent Fibroblast Senescence.
Laliberté C, Bossé B, Bourdeau V, Prieto LI, Perron-Deshaies G, Vuong-Robillard N, Igelmann S, Aguilar LC, Oeffinger M, Baker DJ, DesGroseillers L, Ferbeyre G. Laliberté C, et al. Among authors: baker dj. Biomedicines. 2024 May 14;12(5):1089. doi: 10.3390/biomedicines12051089. Biomedicines. 2024. PMID: 38791051 Free PMC article.
Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood.
Daskalakis NP, Iatrou A, Chatzinakos C, Jajoo A, Snijders C, Wylie D, DiPietro CP, Tsatsani I, Chen CY, Pernia CD, Soliva-Estruch M, Arasappan D, Bharadwaj RA, Collado-Torres L, Wuchty S, Alvarez VE, Dammer EB, Deep-Soboslay A, Duong DM, Eagles N, Huber BR, Huuki L, Holstein VL, Logue MW, Lugenbühl JF, Maihofer AX, Miller MW, Nievergelt CM, Pertea G, Ross D, Sendi MSE, Sun BB, Tao R, Tooke J, Wolf EJ, Zeier Z; PTSD Working Group of Psychiatric Genomics Consortium**; Berretta S, Champagne FA, Hyde T, Seyfried NT, Shin JH, Weinberger DR, Nemeroff CB, Kleinman JE, Ressler KJ; PTSD Working Group of Psychiatric Genomics Consortium. Daskalakis NP, et al. Science. 2024 May 24;384(6698):eadh3707. doi: 10.1126/science.adh3707. Epub 2024 May 24. Science. 2024. PMID: 38781393
Valoctocogene Roxaparvovec.
Levien TL, Baker DE. Levien TL, et al. Among authors: baker de. Hosp Pharm. 2024 Jun;59(3):254-263. doi: 10.1177/00185787231222506. Epub 2024 Jan 4. Hosp Pharm. 2024. PMID: 38764998 Review.
Formulary Drug Review: Rezafungin.
Kessel B, Baker DE. Kessel B, et al. Among authors: baker de. Hosp Pharm. 2024 Jun;59(3):245-253. doi: 10.1177/00185787231206523. Epub 2023 Oct 30. Hosp Pharm. 2024. PMID: 38764996 Review.
Genomic diversity and antimicrobial resistance in clinical Klebsiella pneumoniae isolates from tertiary hospitals in Southern Ghana.
Mills RO, Dadzie I, Le-Viet T, Baker DJ, Addy HPK, Akwetey SA, Donkoh IE, Quansah E, Semanshia PS, Morgan J, Mensah A, Adade NE, Ampah EO, Owusu E, Mwintige P, Amoako EO, Spadar A, Holt KE, Foster-Nyarko E. Mills RO, et al. Among authors: baker dj. J Antimicrob Chemother. 2024 May 16:dkae123. doi: 10.1093/jac/dkae123. Online ahead of print. J Antimicrob Chemother. 2024. PMID: 38751093
Design of High Affinity Binders to Convex Protein Target Sites.
Yang W, Hicks DR, Ghosh A, Schwartze TA, Conventry B, Goreshnik I, Allen A, Halabiya SF, Kim CJ, Hinck CS, Lee DS, Bera AK, Li Z, Wang Y, Schlichthaerle T, Cao L, Huang B, Garrett S, Gerben SR, Rettie S, Heine P, Murray A, Edman N, Carter L, Stewart L, Almo S, Hinck AP, Baker D. Yang W, et al. Among authors: baker d. bioRxiv [Preprint]. 2024 May 2:2024.05.01.592114. doi: 10.1101/2024.05.01.592114. bioRxiv. 2024. PMID: 38746206 Free PMC article. Preprint.
5,658 results