Brekken RA - Search Results

1

Cell Competition Shapes Metastatic Latency and Relapse.

Kim K, Huang H, Parida PK, He L, Marquez-Palencia M, Reese TC, Kapur P, Brugarolas J, Brekken RA, Malladi S. Kim K, et al. Among authors: brekken ra. Cancer Discov. 2023 Jan 9;13(1):85-97. doi: 10.1158/2159-8290.CD-22-0236. Cancer Discov. 2023. PMID: 36098678 Free PMC article.

2

Anti-VEGF therapy revived by c-Met inhibition, but is c-Met the answer?

Lynn KD, Brekken RA. Lynn KD, et al. Among authors: brekken ra. Cancer Discov. 2012 Mar;2(3):211-3. doi: 10.1158/2159-8290.CD-12-0037. Cancer Discov. 2012. PMID: 22585992 Free PMC article.

3

RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas.

Konstantinidou G, Ramadori G, Torti F, Kangasniemi K, Ramirez RE, Cai Y, Behrens C, Dellinger MT, Brekken RA, Wistuba II, Heguy A, Teruya-Feldstein J, Scaglioni PP. Konstantinidou G, et al. Among authors: brekken ra. Cancer Discov. 2013 Apr;3(4):444-57. doi: 10.1158/2159-8290.CD-12-0388. Epub 2013 Jan 28. Cancer Discov. 2013. PMID: 23358651 Free PMC article.

4

Faulty ECM signaling facilitates autoimmune lymphomagenesis.

Brekken RA. Brekken RA. Cancer Discov. 2014 Jan;4(1):25-6. doi: 10.1158/2159-8290.CD-13-0912. Cancer Discov. 2014. PMID: 24402944

5

Extracellular Matrix Induction of Intracellular Reactive Oxygen Species.

Huang H, Du W, Brekken RA. Huang H, et al. Among authors: brekken ra. Antioxid Redox Signal. 2017 Oct 20;27(12):774-784. doi: 10.1089/ars.2017.7305. Antioxid Redox Signal. 2017. PMID: 28791881 Review.

6

Inhibition of Discoidin Domain Receptor 1 Reduces Collagen-mediated Tumorigenicity in Pancreatic Ductal Adenocarcinoma.

Aguilera KY, Huang H, Du W, Hagopian MM, Wang Z, Hinz S, Hwang TH, Wang H, Fleming JB, Castrillon DH, Ren X, Ding K, Brekken RA. Aguilera KY, et al. Among authors: brekken ra. Mol Cancer Ther. 2017 Nov;16(11):2473-2485. doi: 10.1158/1535-7163.MCT-16-0834. Epub 2017 Sep 1. Mol Cancer Ther. 2017. PMID: 28864681 Free PMC article.

7

Cyclooxygenase-2 Inhibition Potentiates the Efficacy of Vascular Endothelial Growth Factor Blockade and Promotes an Immune Stimulatory Microenvironment in Preclinical Models of Pancreatic Cancer.

Zhang Y, Kirane A, Huang H, Sorrelle NB, Burrows FJ, Dellinger MT, Brekken RA. Zhang Y, et al. Among authors: brekken ra. Mol Cancer Res. 2019 Feb;17(2):348-355. doi: 10.1158/1541-7786.MCR-18-0427. Epub 2018 Oct 17. Mol Cancer Res. 2019. PMID: 30333153 Free PMC article.

8

Sitravatinib potentiates immune checkpoint blockade in refractory cancer models.

Du W, Huang H, Sorrelle N, Brekken RA. Du W, et al. Among authors: brekken ra. JCI Insight. 2018 Nov 2;3(21):e124184. doi: 10.1172/jci.insight.124184. JCI Insight. 2018. PMID: 30385724 Free PMC article.

9

Improved Multiplex Immunohistochemistry for Immune Microenvironment Evaluation of Mouse Formalin-Fixed, Paraffin-Embedded Tissues.

Sorrelle N, Ganguly D, Dominguez ATA, Zhang Y, Huang H, Dahal LN, Burton N, Ziemys A, Brekken RA. Sorrelle N, et al. Among authors: brekken ra. J Immunol. 2019 Jan 1;202(1):292-299. doi: 10.4049/jimmunol.1800878. Epub 2018 Dec 3. J Immunol. 2019. PMID: 30510069 Free PMC article.

10

The Next Wave of Stroma-Targeting Therapy in Pancreatic Cancer.

Huang H, Brekken RA. Huang H, et al. Among authors: brekken ra. Cancer Res. 2019 Jan 15;79(2):328-330. doi: 10.1158/0008-5472.CAN-18-3751. Cancer Res. 2019. PMID: 30647067

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