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RAC1-mediated integrin alpha-6 expression in E-cadherin-deficient gastric cancer cells promotes interactions with the stroma and peritoneal dissemination.
Zhang J, Fu L, Wang H, Yonemura A, Semba T, Yasuda-Yoshihara N, Nishimura A, Tajiri T, Tong Y, Yasuda T, Uchihara T, Yamazaki M, Okamoto Y, Yamasaki J, Nagano O, Baba H, Ishimoto T. Zhang J, et al. Among authors: semba t. Cancer Lett. 2024 Jun 1;591:216901. doi: 10.1016/j.canlet.2024.216901. Epub 2024 Apr 17. Cancer Lett. 2024. PMID: 38641311
Phase II Study of the Liposomal Formulation of Eribulin (E7389-LF) in Combination with Nivolumab: Results from the Gastric Cancer Cohort.
Kawazoe A, Yamamoto N, Sugimoto N, Kawakami H, Oshima T, Yamaguchi K, Hino K, Hirao M, Kurokawa Y, Kawakami T, Tsuda M, Hara H, Kaname S, Matsuoka D, Otake Y, Yasuda K, Takase T, Takashima S, Semba T, Muro K. Kawazoe A, et al. Among authors: semba t. Clin Cancer Res. 2024 Apr 1;30(7):1264-1272. doi: 10.1158/1078-0432.CCR-23-1768. Clin Cancer Res. 2024. PMID: 38295160 Free PMC article. Clinical Trial.
Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment.
Yonemura A, Semba T, Zhang J, Fan Y, Yasuda-Yoshihara N, Wang H, Uchihara T, Yasuda T, Nishimura A, Fu L, Hu X, Wei F, Kitamura F, Akiyama T, Yamashita K, Eto K, Iwagami S, Iwatsuki M, Miyamoto Y, Matsusaki K, Yamasaki J, Nagano O, Saya H, Song S, Tan P, Baba H, Ajani JA, Ishimoto T. Yonemura A, et al. Among authors: semba t. Cell Rep. 2024 Jan 23;43(1):113613. doi: 10.1016/j.celrep.2023.113613. Epub 2024 Jan 16. Cell Rep. 2024. PMID: 38232734 Free article.
Phase II Study of the Liposomal Formulation of Eribulin (E7389-LF) in Combination with Nivolumab: Results from the Small Cell Lung Cancer Cohort.
Nishio M, Murakami S, Kawakami H, Okishio K, Tamiya M, Kobayashi H, Fujimoto D, Sugawara S, Kozuki T, Oya Y, Izumi H, Shiroyama T, Satouchi M, Yamamoto N, Kaname S, Matsuoka D, Otake Y, Takase T, Semba T, Azuma K. Nishio M, et al. Among authors: semba t. Cancer Res Commun. 2024 Jan 29;4(1):226-235. doi: 10.1158/2767-9764.CRC-23-0313. Cancer Res Commun. 2024. PMID: 38181055 Free PMC article. Clinical Trial.
Downregulation of 15-PGDH enhances MASH-HCC development via fatty acid-induced T-cell exhaustion.
Hu X, Yasuda T, Yasuda-Yosihara N, Yonemura A, Umemoto T, Nakachi Y, Yamashita K, Semba T, Arima K, Uchihara T, Nishimura A, Bu L, Fu L, Wei F, Zhang J, Tong Y, Wang H, Iwamoto K, Fukuda T, Nakagawa H, Taniguchi K, Miyamoto Y, Baba H, Ishimoto T. Hu X, et al. Among authors: semba t. JHEP Rep. 2023 Aug 23;5(12):100892. doi: 10.1016/j.jhepr.2023.100892. eCollection 2023 Dec. JHEP Rep. 2023. PMID: 37942226 Free PMC article.
Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer.
Kitamura F, Semba T, Yasuda-Yoshihara N, Yamada K, Nishimura A, Yamasaki J, Nagano O, Yasuda T, Yonemura A, Tong Y, Wang H, Akiyama T, Matsumura K, Uemura N, Itoyama R, Bu L, Fu L, Hu X, Wei F, Mima K, Imai K, Hayashi H, Yamashita YI, Miyamoto Y, Baba H, Ishimoto T. Kitamura F, et al. Among authors: semba t. JCI Insight. 2023 Oct 23;8(20):e163022. doi: 10.1172/jci.insight.163022. JCI Insight. 2023. PMID: 37733442 Free PMC article.
Phase Ib/II Study of a Liposomal Formulation of Eribulin (E7389-LF) plus Nivolumab in Patients with Advanced Solid Tumors: Results from Phase Ib.
Ida H, Shimizu T, Nishino M, Nakamura Y, Yazaki S, Katsuya Y, Sato J, Koyama T, Iwasa S, Sudo K, Kondo S, Yonemori K, Shitara K, Shiono S, Matsuoka D, Yasuda K, Otake Y, Suzuki T, Takase T, Takashima S, Yamaguchi K, Semba T, Yamamoto N. Ida H, et al. Among authors: semba t. Cancer Res Commun. 2023 Jul 10;3(7):1189-1199. doi: 10.1158/2767-9764.CRC-22-0401. eCollection 2023 Jul. Cancer Res Commun. 2023. PMID: 37435605 Free PMC article. Clinical Trial.
Cellular senescence induction leads to progressive cell death via the INK4a-RB pathway in naked mole-rats.
Kawamura Y, Oka K, Semba T, Takamori M, Sugiura Y, Yamasaki R, Suzuki Y, Chujo T, Nagase M, Oiwa Y, Fujioka S, Homma S, Yamamura Y, Miyawaki S, Narita M, Fukuda T, Sakai Y, Ishimoto T, Tomizawa K, Suematsu M, Yamamoto T, Bono H, Okano H, Miura K. Kawamura Y, et al. Among authors: semba t. EMBO J. 2023 Aug 15;42(16):e111133. doi: 10.15252/embj.2022111133. Epub 2023 Jul 11. EMBO J. 2023. PMID: 37431790 Free article.
138 results