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Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells.
Vilaplana-Lopera N, Cuminetti V, Almaghrabi R, Papatzikas G, Rout AK, Jeeves M, González E, Alyahyawi Y, Cunningham A, Erdem A, Schnütgen F, Raghavan M, Potluri S, Cazier JB, Schuringa JJ, Reed MAC, Arranz L, Günther UL, Garcia P. Vilaplana-Lopera N, et al. Among authors: gunther ul. Elife. 2022 Sep 2;11:e75908. doi: 10.7554/eLife.75908. Elife. 2022. PMID: 36052997 Free PMC article.
HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells.
Wierenga ATJ, Cunningham A, Erdem A, Lopera NV, Brouwers-Vos AZ, Pruis M, Mulder AB, Günther UL, Martens JHA, Vellenga E, Schuringa JJ. Wierenga ATJ, et al. Among authors: gunther ul. Cancer Metab. 2019 Dec 27;7:11. doi: 10.1186/s40170-019-0206-y. eCollection 2019. Cancer Metab. 2019. PMID: 31890203 Free PMC article.
Dietary methionine starvation impairs acute myeloid leukemia progression.
Cunningham A, Erdem A, Alshamleh I, Geugien M, Pruis M, Pereira-Martins DA, van den Heuvel FAJ, Wierenga ATJ, Ten Berge H, Dennebos R, van den Boom V, Hogeling SM, Weinhäuser I, Knops R, de Blaauw P, Heiner-Fokkema MR, Woolthuis C, Günther UL, Rego EM, Martens JHA, Jansen JH, Schwalbe H, Huls G, Schuringa JJ. Cunningham A, et al. Among authors: gunther ul. Blood. 2022 Nov 10;140(19):2037-2052. doi: 10.1182/blood.2022017575. Blood. 2022. PMID: 35984907 Free article.
Regulation of the Mitochondrion-Fatty Acid Axis for the Metabolic Reprogramming of Chlamydia trachomatis during Treatment with β-Lactam Antimicrobials.
Shima K, Kaufhold I, Eder T, Käding N, Schmidt N, Ogunsulire IM, Deenen R, Köhrer K, Friedrich D, Isay SE, Grebien F, Klinger M, Richer BC, Günther UL, Deepe GS Jr, Rattei T, Rupp J. Shima K, et al. Among authors: gunther ul. mBio. 2021 Mar 30;12(2):e00023-21. doi: 10.1128/mBio.00023-21. mBio. 2021. PMID: 33785629 Free PMC article.
Systems biologists seek fuller integration of systems biology approaches in new cancer research programs.
Wolkenhauer O, Auffray C, Baltrusch S, Blüthgen N, Byrne H, Cascante M, Ciliberto A, Dale T, Drasdo D, Fell D, Ferrell JE Jr, Gallahan D, Gatenby R, Günther U, Harms BD, Herzel H, Junghanss C, Kunz M, van Leeuwen I, Lenormand P, Levi F, Linnebacher M, Lowengrub J, Maini PK, Malik A, Rateitschak K, Sansom O, Schäfer R, Schürrle K, Sers C, Schnell S, Shibata D, Tyson J, Vera J, White M, Zhivotovsky B, Jaster R. Wolkenhauer O, et al. Cancer Res. 2010 Jan 1;70(1):12-3. doi: 10.1158/0008-5472.CAN-09-2676. Epub 2009 Dec 22. Cancer Res. 2010. PMID: 20028868 Free PMC article.
Metabolic and Lipidomic Markers Differentiate COVID-19 From Non-Hospitalized and Other Intensive Care Patients.
Schmelter F, Föh B, Mallagaray A, Rahmöller J, Ehlers M, Lehrian S, von Kopylow V, Künsting I, Lixenfeld AS, Martin E, Ragab M, Meyer-Saraei R, Kreutzmann F, Eitel I, Taube S, Käding N, Jantzen E, Graf T, Sina C, Günther UL. Schmelter F, et al. Among authors: gunther ul. Front Mol Biosci. 2021 Dec 2;8:737039. doi: 10.3389/fmolb.2021.737039. eCollection 2021. Front Mol Biosci. 2021. PMID: 34938772 Free PMC article.
Metabolomics in Cell Biology.
Eraslan Z, Cascante M, Günther UL. Eraslan Z, et al. Among authors: gunther ul. Handb Exp Pharmacol. 2023;277:181-207. doi: 10.1007/164_2022_619. Handb Exp Pharmacol. 2023. PMID: 36456700
The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival.
Stanulović VS, Al Omair S, Reed MAC, Roberts J, Potluri S, Fulton-Ward T, Gudgeon N, Bishop EL, Roels J, Perry TA, Sarkar S, Pratt G, Taghon T, Dimeloe S, Günther UL, Ludwig C, Hoogenkamp M. Stanulović VS, et al. Among authors: gunther ul. Haematologica. 2024 May 30. doi: 10.3324/haematol.2023.283471. Online ahead of print. Haematologica. 2024. PMID: 38813748 Free article.
74 results