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A genetic model for central chondrosarcoma evolution correlates with patient outcome.
Cross W, Lyskjær I, Lesluyes T, Hargreaves S, Strobl AC, Davies C, Waise S, Hames-Fathi S, Oukrif D, Ye H, Amary F, Tirabosco R, Gerrand C, Baker T, Barnes D, Steele C, Alexandrov L, Bond G; Genomics England Research Consortium; Cool P, Pillay N, Van Loo P, Flanagan AM. Cross W, et al. Among authors: steele c. Genome Med. 2022 Aug 30;14(1):99. doi: 10.1186/s13073-022-01084-0. Genome Med. 2022. PMID: 36042521 Free PMC article.
Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways.
Steele CD, Tarabichi M, Oukrif D, Webster AP, Ye H, Fittall M, Lombard P, Martincorena I, Tarpey PS, Collord G, Haase K, Strauss SJ, Berisha F, Vaikkinen H, Dhami P, Jansen M, Behjati S, Amary MF, Tirabosco R, Feber A, Campbell PJ, Alexandrov LB, Van Loo P, Flanagan AM, Pillay N. Steele CD, et al. Cancer Cell. 2019 Mar 18;35(3):441-456.e8. doi: 10.1016/j.ccell.2019.02.002. Cancer Cell. 2019. PMID: 30889380 Free PMC article.
Whole-genome sequencing of single circulating tumor cells from neuroendocrine neoplasms.
Childs A, Steele CD, Vesely C, Rizzo FM, Ensell L, Lowe H, Dhami P, Vaikkinen H, Luong TV, Conde L, Herrero J, Caplin M, Toumpanakis C, Thirlwell C, Hartley JA, Pillay N, Meyer T. Childs A, et al. Among authors: steele cd. Endocr Relat Cancer. 2021 Aug 11;28(9):631-644. doi: 10.1530/ERC-21-0179. Endocr Relat Cancer. 2021. PMID: 34280125 Free PMC article.
Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma.
Zoumpoulidou G, Alvarez-Mendoza C, Mancusi C, Ahmed RM, Denman M, Steele CD, Tarabichi M, Roy E, Davies LR, Manji J, Cristalli C, Scotlandi K, Pillay N, Strauss SJ, Mittnacht S. Zoumpoulidou G, et al. Among authors: steele cd. Nat Commun. 2021 Dec 3;12(1):7064. doi: 10.1038/s41467-021-27291-8. Nat Commun. 2021. PMID: 34862364 Free PMC article.
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA.
Bergstrom EN, Luebeck J, Petljak M, Khandekar A, Barnes M, Zhang T, Steele CD, Pillay N, Landi MT, Bafna V, Mischel PS, Harris RS, Alexandrov LB. Bergstrom EN, et al. Nature. 2022 Feb;602(7897):510-517. doi: 10.1038/s41586-022-04398-6. Epub 2022 Feb 9. Nature. 2022. PMID: 35140399 Free PMC article.
Signatures of copy number alterations in human cancer.
Steele CD, Abbasi A, Islam SMA, Bowes AL, Khandekar A, Haase K, Hames-Fathi S, Ajayi D, Verfaillie A, Dhami P, McLatchie A, Lechner M, Light N, Shlien A, Malkin D, Feber A, Proszek P, Lesluyes T, Mertens F, Flanagan AM, Tarabichi M, Van Loo P, Alexandrov LB, Pillay N. Steele CD, et al. Nature. 2022 Jun;606(7916):984-991. doi: 10.1038/s41586-022-04738-6. Epub 2022 Jun 15. Nature. 2022. PMID: 35705804 Free PMC article.
1,016 results