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Chemically targeting the redox switch in AP1 transcription factor ΔFOSB.
Kumar A, Aglyamova G, Yim YY, Bailey AO, Lynch HM, Powell RT, Nguyen ND, Rosenthal Z, Zhao WN, Li Y, Chen J, Fan S, Lee H, Russell WK, Stephan C, Robison AJ, Haggarty SJ, Nestler EJ, Zhou J, Machius M, Rudenko G. Kumar A, et al. Among authors: machius m. Nucleic Acids Res. 2022 Sep 9;50(16):9548-9567. doi: 10.1093/nar/gkac710. Nucleic Acids Res. 2022. PMID: 36039764 Free PMC article.
Self-assembly of the bZIP transcription factor ΔFosB.
Yin Z, Venkannagari H, Lynch H, Aglyamova G, Bhandari M, Machius M, Nestler EJ, Robison AJ, Rudenko G. Yin Z, et al. Among authors: machius m. Curr Res Struct Biol. 2020;2:1-13. doi: 10.1016/j.crstbi.2019.12.001. Epub 2019 Dec 24. Curr Res Struct Biol. 2020. PMID: 32542236 Free PMC article.
Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity.
Kim MJ, Biag J, Fass DM, Lewis MC, Zhang Q, Fleishman M, Gangwar SP, Machius M, Fromer M, Purcell SM, McCarroll SA, Rudenko G, Premont RT, Scolnick EM, Haggarty SJ. Kim MJ, et al. Among authors: machius m. Mol Psychiatry. 2017 Mar;22(3):417-429. doi: 10.1038/mp.2016.98. Epub 2016 Jul 26. Mol Psychiatry. 2017. PMID: 27457813 Free PMC article.
Three-dimensional structure of the complexin/SNARE complex.
Chen X, Tomchick DR, Kovrigin E, Araç D, Machius M, Südhof TC, Rizo J. Chen X, et al. Among authors: machius m. Neuron. 2002 Jan 31;33(3):397-409. doi: 10.1016/s0896-6273(02)00583-4. Neuron. 2002. PMID: 11832227 Free article.
Structure and mechanism of a eukaryotic FMN adenylyltransferase.
Huerta C, Borek D, Machius M, Grishin NV, Zhang H. Huerta C, et al. Among authors: machius m. J Mol Biol. 2009 Jun 5;389(2):388-400. doi: 10.1016/j.jmb.2009.04.022. Epub 2009 Apr 16. J Mol Biol. 2009. PMID: 19375431 Free PMC article.
86 results