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Chemically targeting the redox switch in AP1 transcription factor ΔFOSB.
Kumar A, Aglyamova G, Yim YY, Bailey AO, Lynch HM, Powell RT, Nguyen ND, Rosenthal Z, Zhao WN, Li Y, Chen J, Fan S, Lee H, Russell WK, Stephan C, Robison AJ, Haggarty SJ, Nestler EJ, Zhou J, Machius M, Rudenko G. Kumar A, et al. Among authors: haggarty sj. Nucleic Acids Res. 2022 Sep 9;50(16):9548-9567. doi: 10.1093/nar/gkac710. Nucleic Acids Res. 2022. PMID: 36039764 Free PMC article.
Antidepressant actions of histone deacetylase inhibitors.
Covington HE 3rd, Maze I, LaPlant QC, Vialou VF, Ohnishi YN, Berton O, Fass DM, Renthal W, Rush AJ 3rd, Wu EY, Ghose S, Krishnan V, Russo SJ, Tamminga C, Haggarty SJ, Nestler EJ. Covington HE 3rd, et al. Among authors: haggarty sj. J Neurosci. 2009 Sep 16;29(37):11451-60. doi: 10.1523/JNEUROSCI.1758-09.2009. J Neurosci. 2009. PMID: 19759294 Free PMC article.
Essential role of the histone methyltransferase G9a in cocaine-induced plasticity.
Maze I, Covington HE 3rd, Dietz DM, LaPlant Q, Renthal W, Russo SJ, Mechanic M, Mouzon E, Neve RL, Haggarty SJ, Ren Y, Sampath SC, Hurd YL, Greengard P, Tarakhovsky A, Schaefer A, Nestler EJ. Maze I, et al. Among authors: haggarty sj. Science. 2010 Jan 8;327(5962):213-6. doi: 10.1126/science.1179438. Science. 2010. PMID: 20056891 Free PMC article.
Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity.
Kim MJ, Biag J, Fass DM, Lewis MC, Zhang Q, Fleishman M, Gangwar SP, Machius M, Fromer M, Purcell SM, McCarroll SA, Rudenko G, Premont RT, Scolnick EM, Haggarty SJ. Kim MJ, et al. Among authors: haggarty sj. Mol Psychiatry. 2017 Mar;22(3):417-429. doi: 10.1038/mp.2016.98. Epub 2016 Jul 26. Mol Psychiatry. 2017. PMID: 27457813 Free PMC article.
167 results