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An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections.
Parker EN, Cain BN, Hajian B, Ulrich RJ, Geddes EJ, Barkho S, Lee HY, Williams JD, Raynor M, Caridha D, Zaino A, Shekhar M, Muñoz KA, Rzasa KM, Temple ER, Hunt D, Jin X, Vuong C, Pannone K, Kelly AM, Mulligan MP, Lee KK, Lau GW, Hung DT, Hergenrother PJ. Parker EN, et al. Among authors: hajian b. ACS Cent Sci. 2022 Aug 24;8(8):1145-1158. doi: 10.1021/acscentsci.2c00598. Epub 2022 Aug 10. ACS Cent Sci. 2022. PMID: 36032774 Free PMC article.
Correction to "An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections".
Parker EN, Cain BN, Hajian B, Ulrich RJ, Geddes EJ, Barkho S, Lee HY, Williams JD, Raynor M, Caridha D, Zaino A, Rohde JM, Zak M, Shekhar M, Muñoz KA, Rzasa KM, Temple ER, Hunt D, Jin X, Vuong C, Pannone K, Kelly AM, Mulligan MP, Lee KK, Lau GW, Hung DT, Hergenrother PJ. Parker EN, et al. Among authors: hajian b. ACS Cent Sci. 2022 Sep 28;8(9):1362. doi: 10.1021/acscentsci.2c00969. Epub 2022 Sep 6. ACS Cent Sci. 2022. PMID: 36188352 Free PMC article.
MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.
Reeve SM, Scocchera EW, G-Dayanadan N, Keshipeddy S, Krucinska J, Hajian B, Ferreira J, Nailor M, Aeschlimann J, Wright DL, Anderson AC. Reeve SM, et al. Among authors: hajian b. Cell Chem Biol. 2016 Dec 22;23(12):1458-1467. doi: 10.1016/j.chembiol.2016.11.007. Epub 2016 Dec 8. Cell Chem Biol. 2016. PMID: 27939900 Free PMC article.
Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex.
Kwon JJ, Hajian B, Bian Y, Young LC, Amor AJ, Fuller JR, Fraley CV, Sykes AM, So J, Pan J, Baker L, Lee SJ, Wheeler DB, Mayhew DL, Persky NS, Yang X, Root DE, Barsotti AM, Stamford AW, Perry CK, Burgin A, McCormick F, Lemke CT, Hahn WC, Aguirre AJ. Kwon JJ, et al. Among authors: hajian b. Nature. 2022 Sep;609(7926):408-415. doi: 10.1038/s41586-022-04928-2. Epub 2022 Jul 13. Nature. 2022. PMID: 35831509 Free PMC article.
Discovery of a structural class of antibiotics with explainable deep learning.
Wong F, Zheng EJ, Valeri JA, Donghia NM, Anahtar MN, Omori S, Li A, Cubillos-Ruiz A, Krishnan A, Jin W, Manson AL, Friedrichs J, Helbig R, Hajian B, Fiejtek DK, Wagner FF, Soutter HH, Earl AM, Stokes JM, Renner LD, Collins JJ. Wong F, et al. Among authors: hajian b. Nature. 2024 Feb;626(7997):177-185. doi: 10.1038/s41586-023-06887-8. Epub 2023 Dec 20. Nature. 2024. PMID: 38123686
Reference values for six-minute walk distance and six-minute walk work in Caucasian adults.
Delbressine JM, Jensen D, Vaes AW, Li PZ, Bourbeau J, Tan WC, Hajian B, van 't Hul AJ, Spruit MA; CanCOLD Collaborative Research Group and the Canadian Respiratory Research Network. Delbressine JM, et al. Among authors: hajian b. Pulmonology. 2023 Sep-Oct;29(5):399-409. doi: 10.1016/j.pulmoe.2023.02.014. Epub 2023 Apr 10. Pulmonology. 2023. PMID: 37045743 Free article.
Impact of Coronavirus Disease 2019-Related Infection Prevention and Control Measures on the Occurrence of COPD Exacerbations During Inpatient Pulmonary Rehabilitation.
Waeijen-Smit K, Houben-Wilke S, Posthuma R, de Jong F, Janssen DJA, van Loon NPH, Hajian B, Simons SO, Spruit MA, Franssen FME. Waeijen-Smit K, et al. Among authors: hajian b. Chronic Obstr Pulm Dis. 2023 Apr 27;10(2):127-138. doi: 10.15326/jcopdf.2022.0345. Chronic Obstr Pulm Dis. 2023. PMID: 36599097 Free PMC article.
24 results