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Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19.
Assmus F, Driouich JS, Abdelnabi R, Vangeel L, Touret F, Adehin A, Chotsiri P, Cochin M, Foo CS, Jochmans D, Kim S, Luciani L, Moureau G, Park S, Pétit PR, Shum D, Wattanakul T, Weynand B, Fraisse L, Ioset JR, Mowbray CE, Owen A, Hoglund RM, Tarning J, Lamballerie X, Nougairède A, Neyts J, Sjö P, Escudié F, Scandale I, Chatelain E. Assmus F, et al. Among authors: chatelain e. Microorganisms. 2022 Aug 12;10(8):1639. doi: 10.3390/microorganisms10081639. Microorganisms. 2022. PMID: 36014057 Free PMC article.
Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides.
Thompson AM, Marshall AJ, Maes L, Yarlett N, Bacchi CJ, Gaukel E, Wring SA, Launay D, Braillard S, Chatelain E, Mowbray CE, Denny WA. Thompson AM, et al. Among authors: chatelain e. Bioorg Med Chem Lett. 2018 Jan 15;28(2):207-213. doi: 10.1016/j.bmcl.2017.10.067. Epub 2017 Oct 27. Bioorg Med Chem Lett. 2018. PMID: 29191556 Free PMC article.
In vitro and in vivo pharmacodynamics of three novel antileishmanial lead series.
Van den Kerkhof M, Mabille D, Chatelain E, Mowbray CE, Braillard S, Hendrickx S, Maes L, Caljon G. Van den Kerkhof M, et al. Among authors: chatelain e. Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):81-86. doi: 10.1016/j.ijpddr.2018.01.006. Epub 2018 Jan 31. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29425734 Free PMC article.
Identification of Resistance Determinants for a Promising Antileishmanial Oxaborole Series.
Van den Kerkhof M, Leprohon P, Mabille D, Hendrickx S, Tulloch LB, Wall RJ, Wyllie S, Chatelain E, Mowbray CE, Braillard S, Ouellette M, Maes L, Caljon G. Van den Kerkhof M, et al. Among authors: chatelain e. Microorganisms. 2021 Jun 29;9(7):1408. doi: 10.3390/microorganisms9071408. Microorganisms. 2021. PMID: 34210040 Free PMC article.
The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern.
Abdelnabi R, Foo CS, Jochmans D, Vangeel L, De Jonghe S, Augustijns P, Mols R, Weynand B, Wattanakul T, Hoglund RM, Tarning J, Mowbray CE, Sjö P, Escudié F, Scandale I, Chatelain E, Neyts J. Abdelnabi R, et al. Among authors: chatelain e. Nat Commun. 2022 Feb 15;13(1):719. doi: 10.1038/s41467-022-28354-0. Nat Commun. 2022. PMID: 35169114 Free PMC article.
Pre-clinical evaluation of antiviral activity of nitazoxanide against SARS-CoV-2.
Driouich JS, Cochin M, Touret F, Petit PR, Gilles M, Moureau G, Barthélémy K, Laprie C, Wattanakul T, Chotsiri P, Hoglund RM, Tarning J, Fraisse L, Sjö P, Mowbray CE, Escudié F, Scandale I, Chatelain E, de Lamballerie X, Solas C, Nougairède A. Driouich JS, et al. Among authors: chatelain e. EBioMedicine. 2022 Aug;82:104148. doi: 10.1016/j.ebiom.2022.104148. Epub 2022 Jul 11. EBioMedicine. 2022. PMID: 35834886 Free PMC article.
123 results