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LC-MS bioanalysis of Trastuzumab and released emtansine using nano-surface and molecular-orientation limited (nSMOL) proteolysis and liquid-liquid partition in plasma of Trastuzumab emtansine-treated breast cancer patients.
Iwamoto N, Shimomura A, Tamura K, Hamada A, Shimada T. Iwamoto N, et al. Among authors: hamada a. J Pharm Biomed Anal. 2017 Oct 25;145:33-39. doi: 10.1016/j.jpba.2017.06.032. Epub 2017 Jun 19. J Pharm Biomed Anal. 2017. PMID: 28648785 Free article.
Validated LC-MS/MS analysis of immune checkpoint inhibitor Nivolumab in human plasma using a Fab peptide-selective quantitation method: nano-surface and molecular-orientation limited (nSMOL) proteolysis.
Iwamoto N, Shimada T, Terakado H, Hamada A. Iwamoto N, et al. Among authors: hamada a. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jun 15;1023-1024:9-16. doi: 10.1016/j.jchromb.2016.04.038. Epub 2016 Apr 27. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 27155936 Free article.
Use of an alternative signature peptide during development of a LC-MS/MS assay of plasma nivolumab levels applicable for multiple species.
Ohuchi M, Yagishita S, Taguchi K, Goto Y, Fukahori M, Enoki Y, Shimada T, Yamaguchi M, Matsumoto K, Hamada A. Ohuchi M, et al. Among authors: hamada a. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Jan 1;1162:122489. doi: 10.1016/j.jchromb.2020.122489. Epub 2020 Dec 8. J Chromatogr B Analyt Technol Biomed Life Sci. 2021. PMID: 33385769
603 results