Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

49 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV-2.
Santos LH, Kronenberger T, Almeida RG, Silva EB, Rocha REO, Oliveira JC, Barreto LV, Skinner D, Fajtová P, Giardini MA, Woodworth B, Bardine C, Lourenço AL, Craik CS, Poso A, Podust LM, McKerrow JH, Siqueira-Neto JL, O'Donoghue AJ, da Silva Júnior EN, Ferreira RS. Santos LH, et al. Among authors: lourenco al. J Chem Inf Model. 2022 Dec 26;62(24):6553-6573. doi: 10.1021/acs.jcim.2c00693. Epub 2022 Aug 12. J Chem Inf Model. 2022. PMID: 35960688
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells.
Mahoney M, Damalanka VC, Tartell MA, Chung DH, Lourenço AL, Pwee D, Mayer Bridwell AE, Hoffmann M, Voss J, Karmakar P, Azouz NP, Klingler AM, Rothlauf PW, Thompson CE, Lee M, Klampfer L, Stallings CL, Rothenberg ME, Pöhlmann S, Whelan SPJ, O'Donoghue AJ, Craik CS, Janetka JW. Mahoney M, et al. Among authors: lourenco al. Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2108728118. doi: 10.1073/pnas.2108728118. Proc Natl Acad Sci U S A. 2021. PMID: 34635581 Free PMC article.
In Vivo Measurement of Granzyme Proteolysis from Activated Immune Cells with PET.
Zhao N, Bardine C, Lourenço AL, Wang YH, Huang Y, Cleary SJ, Wilson DM, Oh DY, Fong L, Looney MR, Evans MJ, Craik CS. Zhao N, et al. Among authors: lourenco al. ACS Cent Sci. 2021 Oct 27;7(10):1638-1649. doi: 10.1021/acscentsci.1c00529. Epub 2021 Sep 2. ACS Cent Sci. 2021. PMID: 34729407 Free PMC article.
Synthesis and mechanistic evaluation of novel N'-benzylidene-carbohydrazide-1H-pyrazolo[3,4-b]pyridine derivatives as non-anionic antiplatelet agents.
Lourenço AL, Salvador RRS, Silva LA, Saito MS, Mello JFR, Cabral LM, Rodrigues CR, Vera MAF, Muri EMF, de Souza AMT, Craik CS, Dias LRS, Castro HC, Sathler PC. Lourenço AL, et al. Eur J Med Chem. 2017 Jul 28;135:213-229. doi: 10.1016/j.ejmech.2017.04.023. Epub 2017 Apr 14. Eur J Med Chem. 2017. PMID: 28453995
Identification of a potential lead structure for designing new antimicrobials to treat infections caused by Staphylococcus epidermidis-resistant strains.
Pinheiro LC, Abreu PA, Afonso IF, Leal B, Corrêa LC, Borges JC, Marques IP, Lourenço AL, Sathler P, dos Santos AL, Medeiros CA, Cabral LM, Júnior ML, Romeiro GA, Ferreira VF, Rodrigues CR, Castro HC, Bernardino AM. Pinheiro LC, et al. Among authors: lourenco al. Curr Microbiol. 2008 Nov;57(5):463-8. doi: 10.1007/s00284-008-9234-5. Epub 2008 Sep 23. Curr Microbiol. 2008. PMID: 18810543
Exploring N-acylhydrazone derivatives against clinical resistant bacterial strains.
Lannes AC, Leal B, Novais JS, Lione V, Monteiro GC, Lourenço AL, Sathler PC, Jordão AK, Rodrigues CR, Cabral LM, Cunha AC, Campos V, Ferreira VF, de Souza MC, Santos DO, Castro HC. Lannes AC, et al. Among authors: lourenco al. Curr Microbiol. 2014 Sep;69(3):357-64. doi: 10.1007/s00284-014-0591-y. Epub 2014 May 8. Curr Microbiol. 2014. PMID: 24807624
49 results