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Epigenetic reader SP140 loss of function drives Crohn's disease due to uncontrolled macrophage topoisomerases.
Amatullah H, Fraschilla I, Digumarthi S, Huang J, Adiliaghdam F, Bonilla G, Wong LP, Rivard ME, Beauchamp C, Mercier V, Goyette P, Sadreyev RI, Anthony RM, Rioux JD, Jeffrey KL. Amatullah H, et al. Among authors: sadreyev ri. Cell. 2022 Aug 18;185(17):3232-3247.e18. doi: 10.1016/j.cell.2022.06.048. Epub 2022 Aug 10. Cell. 2022. PMID: 35952671 Free PMC article.
HELZ2 Is an IFN Effector Mediating Suppression of Dengue Virus.
Fusco DN, Pratt H, Kandilas S, Cheon SS, Lin W, Cronkite DA, Basavappa M, Jeffrey KL, Anselmo A, Sadreyev R, Yapp C, Shi X, O'Sullivan JF, Gerszten RE, Tomaru T, Yoshino S, Satoh T, Chung RT. Fusco DN, et al. Front Microbiol. 2017 Feb 20;8:240. doi: 10.3389/fmicb.2017.00240. eCollection 2017. Front Microbiol. 2017. PMID: 28265266 Free PMC article.
Maintenance of macrophage transcriptional programs and intestinal homeostasis by epigenetic reader SP140.
Mehta S, Cronkite DA, Basavappa M, Saunders TL, Adiliaghdam F, Amatullah H, Morrison SA, Pagan JD, Anthony RM, Tonnerre P, Lauer GM, Lee JC, Digumarthi S, Pantano L, Ho Sui SJ, Ji F, Sadreyev R, Zhou C, Mullen AC, Kumar V, Li Y, Wijmenga C, Xavier RJ, Means TK, Jeffrey KL. Mehta S, et al. Sci Immunol. 2017 Mar 3;2(9):eaag3160. doi: 10.1126/sciimmunol.aag3160. Epub 2017 Mar 3. Sci Immunol. 2017. PMID: 28783698 Free PMC article.
Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells.
Frodermann V, Rohde D, Courties G, Severe N, Schloss MJ, Amatullah H, McAlpine CS, Cremer S, Hoyer FF, Ji F, van Koeverden ID, Herisson F, Honold L, Masson GS, Zhang S, Grune J, Iwamoto Y, Schmidt SP, Wojtkiewicz GR, Lee IH, Gustafsson K, Pasterkamp G, de Jager SCA, Sadreyev RI, MacFadyen J, Libby P, Ridker P, Scadden DT, Naxerova K, Jeffrey KL, Swirski FK, Nahrendorf M. Frodermann V, et al. Among authors: sadreyev ri. Nat Med. 2019 Nov;25(11):1761-1771. doi: 10.1038/s41591-019-0633-x. Epub 2019 Nov 7. Nat Med. 2019. PMID: 31700184 Free PMC article.
Alterations in Fecal Microbiomes and Serum Metabolomes of Fatigued Patients With Quiescent Inflammatory Bowel Diseases.
Borren NZ, Plichta D, Joshi AD, Bonilla G, Peng V, Colizzo FP, Luther J, Khalili H, Garber JJ, Janneke van der Woude C, Sadreyev R, Vlamakis H, Xavier RJ, Ananthakrishnan AN. Borren NZ, et al. Clin Gastroenterol Hepatol. 2021 Mar;19(3):519-527.e5. doi: 10.1016/j.cgh.2020.03.013. Epub 2020 Mar 14. Clin Gastroenterol Hepatol. 2021. PMID: 32184182
Growth Hormone Releasing Hormone Reduces Circulating Markers of Immune Activation in Parallel with Effects on Hepatic Immune Pathways in Individuals with HIV-infection and Nonalcoholic Fatty Liver Disease.
Stanley TL, Fourman LT, Wong LP, Sadreyev R, Billingsley JM, Feldpausch MN, Zheng I, Pan CS, Boutin A, Lee H, Corey KE, Torriani M, Kleiner DE, Chung RT, Hadigan CM, Grinspoon SK. Stanley TL, et al. Clin Infect Dis. 2021 Aug 16;73(4):621-630. doi: 10.1093/cid/ciab019. Clin Infect Dis. 2021. PMID: 33852720 Free PMC article. Clinical Trial.
Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease.
McAlpine CS, Park J, Griciuc A, Kim E, Choi SH, Iwamoto Y, Kiss MG, Christie KA, Vinegoni C, Poller WC, Mindur JE, Chan CT, He S, Janssen H, Wong LP, Downey J, Singh S, Anzai A, Kahles F, Jorfi M, Feruglio PF, Sadreyev RI, Weissleder R, Kleinstiver BP, Nahrendorf M, Tanzi RE, Swirski FK. McAlpine CS, et al. Among authors: sadreyev ri. Nature. 2021 Jul;595(7869):701-706. doi: 10.1038/s41586-021-03734-6. Epub 2021 Jul 14. Nature. 2021. PMID: 34262178 Free PMC article.
Type I, II, and III Interferon Signatures Correspond to Coronavirus Disease 2019 Severity.
Kim MH, Salloum S, Wang JY, Wong LP, Regan J, Lefteri K, Manickas-Hill Z, Gao C, Li JZ, Sadreyev RI, Yu XG, Chung RT; MGH COVID-19 Collection & Processing Team. Kim MH, et al. Among authors: sadreyev ri. J Infect Dis. 2021 Sep 1;224(5):777-782. doi: 10.1093/infdis/jiab288. J Infect Dis. 2021. PMID: 34467988 Free PMC article.
178 results