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Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus.
Ojeda-Juárez D, Lawrence JA, Soldau K, Pizzo DP, Wheeler E, Aguilar-Calvo P, Khuu H, Chen J, Malik A, Funk G, Nam P, Sanchez H, Geschwind MD, Wu C, Yeo GW, Chen X, Patrick GN, Sigurdson CJ. Ojeda-Juárez D, et al. Among authors: lawrence ja. Neurobiol Dis. 2022 Oct 1;172:105834. doi: 10.1016/j.nbd.2022.105834. Epub 2022 Jul 26. Neurobiol Dis. 2022. PMID: 35905927 Free PMC article.
Enhanced neuroinvasion by smaller, soluble prions.
Bett C, Lawrence J, Kurt TD, Orru C, Aguilar-Calvo P, Kincaid AE, Surewicz WK, Caughey B, Wu C, Sigurdson CJ. Bett C, et al. Acta Neuropathol Commun. 2017 Apr 21;5(1):32. doi: 10.1186/s40478-017-0430-z. Acta Neuropathol Commun. 2017. PMID: 28431576 Free PMC article.
Generation of novel neuroinvasive prions following intravenous challenge.
Aguilar-Calvo P, Bett C, Sevillano AM, Kurt TD, Lawrence J, Soldau K, Hammarström P, Nilsson KPR, Sigurdson CJ. Aguilar-Calvo P, et al. Brain Pathol. 2018 Nov;28(6):999-1011. doi: 10.1111/bpa.12598. Epub 2018 Jul 5. Brain Pathol. 2018. PMID: 29505163 Free PMC article.
Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease.
Sevillano AM, Aguilar-Calvo P, Kurt TD, Lawrence JA, Soldau K, Nam TH, Schumann T, Pizzo DP, Nyström S, Choudhury B, Altmeppen H, Esko JD, Glatzel M, Nilsson KPR, Sigurdson CJ. Sevillano AM, et al. Among authors: lawrence ja. J Clin Invest. 2020 Mar 2;130(3):1350-1362. doi: 10.1172/JCI131564. J Clin Invest. 2020. PMID: 31985492 Free PMC article.
Diminished Neuronal ESCRT-0 Function Exacerbates AMPA Receptor Derangement and Accelerates Prion-Induced Neurodegeneration.
Lawrence JA, Aguilar-Calvo P, Ojeda-Juárez D, Khuu H, Soldau K, Pizzo DP, Wang J, Malik A, Shay TF, Sullivan EE, Aulston B, Song SM, Callender JA, Sanchez H, Geschwind MD, Roy S, Rissman RA, Trejo J, Tanaka N, Wu C, Chen X, Patrick GN, Sigurdson CJ. Lawrence JA, et al. J Neurosci. 2023 May 24;43(21):3970-3984. doi: 10.1523/JNEUROSCI.1878-22.2023. Epub 2023 Apr 5. J Neurosci. 2023. PMID: 37019623 Free PMC article.
Leveraging a smartphone to perform time-gated luminescence measurements.
Fratto BE, Culver EL, Davis G, Deans R, Goods JB, Hwang S, Keller NK, Lawrence JA 3rd, Petty AR, Swager TM, Walish JJ, Zhu Z, Cox JR. Fratto BE, et al. Among authors: lawrence ja 3rd. PLoS One. 2023 Oct 30;18(10):e0293740. doi: 10.1371/journal.pone.0293740. eCollection 2023. PLoS One. 2023. PMID: 37903097 Free PMC article.
190 results