Gazarini ML - Search Results

1

Synthesis, Structure−Activity Relationships, and Parasitological Profiling of Brussonol Derivatives as New Plasmodium falciparum Inhibitors.

Barbosa CS, Ahmad A, Maluf SEC, Moura IMR, Souza GE, Guerra GAH, Barros RRM, Gazarini ML, Aguiar ACC, Burtoloso ACB, Guido RVC. Barbosa CS, et al. Among authors: gazarini ml. Pharmaceuticals (Basel). 2022 Jun 30;15(7):814. doi: 10.3390/ph15070814. Pharmaceuticals (Basel). 2022. PMID: 35890113 Free PMC article.

2

KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.

González-Bacerio J, Maluf SEC, Méndez Y, Pascual I, Florent I, Melo PMS, Budu A, Ferreira JC, Moreno E, Carmona AK, Rivera DG, Alonso Del Rivero M, Gazarini ML. González-Bacerio J, et al. Among authors: gazarini ml. Bioorg Med Chem. 2017 Sep 1;25(17):4628-4636. doi: 10.1016/j.bmc.2017.06.047. Epub 2017 Jul 4. Bioorg Med Chem. 2017. PMID: 28728898

3

Improvement of antimalarial activity of a 3-alkylpiridine alkaloid analog by replacing the pyridine ring to a thiazole-containing heterocycle: Mode of action, mutagenicity profile, and Caco-2 cell-based permeability.

Guimarães DSM, de Sousa Luz LS, do Nascimento SB, Silva LR, de Miranda Martins NR, de Almeida HG, de Souza Reis V, Maluf SEC, Budu A, Marinho JA, Abramo C, Carmona AK, da Silva MG, da Silva GR, Kemmer VM, Butera AP, Ribeiro-Viana RM, Gazarini ML, Júnior CSN, Guimarães L, Dos Santos FV, de Castro WV, Viana GHR, de Brito CFA, de Pilla Varotti F. Guimarães DSM, et al. Among authors: gazarini ml. Eur J Pharm Sci. 2019 Oct 1;138:105015. doi: 10.1016/j.ejps.2019.105015. Epub 2019 Jul 22. Eur J Pharm Sci. 2019. PMID: 31344442

4

Overexpression of Plasmodium falciparum M1 Aminopeptidase Promotes an Increase in Intracellular Proteolysis and Modifies the Asexual Erythrocytic Cycle Development.

Hoff CC, Azevedo MF, Thurler AB, Maluf SEC, Melo PMS, Del Rivero MA, González-Bacerio J, Carmona AK, Budu A, Gazarini ML. Hoff CC, et al. Among authors: gazarini ml. Pathogens. 2021 Nov 10;10(11):1452. doi: 10.3390/pathogens10111452. Pathogens. 2021. PMID: 34832608 Free PMC article.

5

Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues.

Cortopassi WA, Gunderson E, Annunciato Y, Silva AES, Dos Santos Ferreira A, Garcia Teles CB, Pimentel AS, Ramamoorthi R, Gazarini ML, Meneghetti MR, Guido RVC, Pereira DB, Jacobson MP, Krettli AU, Caroline C Aguiar A. Cortopassi WA, et al. Among authors: gazarini ml. Int J Parasitol Drugs Drug Resist. 2022 Dec;20:121-128. doi: 10.1016/j.ijpddr.2022.10.003. Epub 2022 Oct 31. Int J Parasitol Drugs Drug Resist. 2022. PMID: 36375339 Free PMC article.

6

South American rattlesnake cationic polypeptide crotamine trafficking dynamic in Plasmodium falciparum-infected erythrocytes: Pharmacological inhibitors, parasite cycle and incubation time influences in uptake.

El Chamy Maluf S, Hayashi MAF, Campeiro JD, Oliveira EB, Gazarini ML, Carmona AK. El Chamy Maluf S, et al. Among authors: gazarini ml. Toxicon. 2022 Mar;208:47-52. doi: 10.1016/j.toxicon.2022.01.006. Epub 2022 Jan 22. Toxicon. 2022. PMID: 35074306

7

Chondroitin Sulfate Protects the Liver in an Experimental Model of Extra-Hepatic Cholestasis Induced by Common Bile Duct Ligation.

Guedes PLR, Carvalho CPF, Carbonel AAF, Simões MJ, Icimoto MY, Aguiar JAK, Kouyoumdjian M, Gazarini ML, Nagaoka MR. Guedes PLR, et al. Among authors: gazarini ml. Molecules. 2022 Jan 20;27(3):654. doi: 10.3390/molecules27030654. Molecules. 2022. PMID: 35163920 Free PMC article.

8

Inhibition of Plasmodium falciparum cysteine proteases by the sugarcane cystatin CaneCPI-4.

Melo PMS, El Chamy Maluf S, Azevedo MF, Paschoalin T, Budu A, Bagnaresi P, Henrique-Silva F, Soares-Costa A, Gazarini ML, Carmona AK. Melo PMS, et al. Among authors: gazarini ml. Parasitol Int. 2018 Apr;67(2):233-236. doi: 10.1016/j.parint.2017.12.005. Epub 2017 Dec 27. Parasitol Int. 2018. PMID: 29288140

9

Human plasma plasminogen internalization route in Plasmodium falciparum-infected erythrocytes.

El Chamy Maluf S, Icimoto MY, Melo PMS, Budu A, Coimbra R, Gazarini ML, Carmona AK. El Chamy Maluf S, et al. Among authors: gazarini ml. Malar J. 2020 Aug 26;19(1):302. doi: 10.1186/s12936-020-03377-4. Malar J. 2020. PMID: 32847585 Free PMC article.

10

Metabolites from Marine Sponges and Their Potential to Treat Malarial Protozoan Parasites Infection: A Systematic Review.

Aguiar ACC, Parisi JR, Granito RN, de Sousa LRF, Renno ACM, Gazarini ML. Aguiar ACC, et al. Among authors: gazarini ml. Mar Drugs. 2021 Feb 28;19(3):134. doi: 10.3390/md19030134. Mar Drugs. 2021. PMID: 33670878 Free PMC article.

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