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Unusual dimeric flavonoids (brachydins) induce ultrastructural membrane alterations associated with antitumor activity in cancer cell lines.
Maciel-Silva VL, da Rocha CQ, Alencar LMR, Castelo-Branco PV, Sousa IH, Azevedo-Santos AP, Vale AAM, Monteiro SG, Soares RP, Guimarães SJA, Nascimento JRD, Pereira SRF. Maciel-Silva VL, et al. Among authors: castelo branco pv. Drug Chem Toxicol. 2023 Nov;46(4):665-676. doi: 10.1080/01480545.2022.2080217. Epub 2022 May 29. Drug Chem Toxicol. 2023. PMID: 35635136
Ascorbic acid reduces the genetic damage caused by miltefosine (hexadecylphosphocholine) in animals infected by Leishmania (Leishamnia) infantum without decreasing its antileishmanial activity.
Castelo-Branco PV, Alves HJ, Pontes RL, Maciel-Silva VL, Ferreira Pereira SR. Castelo-Branco PV, et al. Int J Parasitol Drugs Drug Resist. 2019 Apr;9:8-15. doi: 10.1016/j.ijpddr.2018.12.002. Epub 2018 Dec 13. Int J Parasitol Drugs Drug Resist. 2019. PMID: 30578864 Free PMC article.
River waters near to agricultural sites in the Northeastern Brazil (Maranhão State) cause genetic damage in Nile Tilapia (Oreochromis niloticus).
Castro MS, Luvizotto-Santos R, Pereira SRF, Moreira VR, Castelo-Branco PV, Silva VLM, Carvalho-Costa LF. Castro MS, et al. Among authors: castelo branco pv. Braz J Biol. 2019 Apr-Jun;79(2):365-367. doi: 10.1590/1519-6984.184337. Epub 2018 Aug 20. Braz J Biol. 2019. PMID: 30133558 Free article. No abstract available.