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A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes.
Girdhar K, Huang Q, Chow IT, Vatanen T, Brady C, Raisingani A, Autissier P, Atkinson MA, Kwok WW, Kahn CR, Altindis E. Girdhar K, et al. Among authors: atkinson ma. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2120028119. doi: 10.1073/pnas.2120028119. Epub 2022 Jul 25. Proc Natl Acad Sci U S A. 2022. PMID: 35878027 Free PMC article.
Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice.
Parker MJ, Xue S, Alexander JJ, Wasserfall CH, Campbell-Thompson ML, Battaglia M, Gregori S, Mathews CE, Song S, Troutt M, Eisenbeis S, Williams J, Schatz DA, Haller MJ, Atkinson MA. Parker MJ, et al. Among authors: atkinson ma. Diabetes. 2009 Oct;58(10):2277-84. doi: 10.2337/db09-0557. Epub 2009 Jul 23. Diabetes. 2009. PMID: 19628781 Free PMC article.
Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes.
Michels AW, Landry LG, McDaniel KA, Yu L, Campbell-Thompson M, Kwok WW, Jones KL, Gottlieb PA, Kappler JW, Tang Q, Roep BO, Atkinson MA, Mathews CE, Nakayama M. Michels AW, et al. Among authors: atkinson ma. Diabetes. 2017 Mar;66(3):722-734. doi: 10.2337/db16-1025. Epub 2016 Dec 5. Diabetes. 2017. PMID: 27920090 Free PMC article.
Human islet T cells are highly reactive to preproinsulin in type 1 diabetes.
Anderson AM, Landry LG, Alkanani AA, Pyle L, Powers AC, Atkinson MA, Mathews CE, Roep BO, Michels AW, Nakayama M. Anderson AM, et al. Among authors: atkinson ma. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2107208118. doi: 10.1073/pnas.2107208118. Proc Natl Acad Sci U S A. 2021. PMID: 34611019 Free PMC article.
Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion.
Goudy KS, Burkhardt BR, Wasserfall C, Song S, Campbell-Thompson ML, Brusko T, Powers MA, Clare-Salzler MJ, Sobel ES, Ellis TM, Flotte TR, Atkinson MA. Goudy KS, et al. Among authors: atkinson ma. J Immunol. 2003 Sep 1;171(5):2270-8. doi: 10.4049/jimmunol.171.5.2270. J Immunol. 2003. PMID: 12928371
512 results