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Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine.
Singh AK, De Wijngaert B, Bijnens M, Uyttersprot K, Nguyen H, Martinez SE, Schols D, Herdewijn P, Pannecouque C, Arnold E, Das K. Singh AK, et al. Among authors: pannecouque c. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2203660119. doi: 10.1073/pnas.2203660119. Epub 2022 Jul 19. Proc Natl Acad Sci U S A. 2022. PMID: 35858448 Free PMC article.
Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents.
Wu T, Froeyen M, Kempeneers V, Pannecouque C, Wang J, Busson R, De Clercq E, Herdewijn P. Wu T, et al. Among authors: pannecouque c. J Am Chem Soc. 2005 Apr 13;127(14):5056-65. doi: 10.1021/ja043045z. J Am Chem Soc. 2005. PMID: 15810840
Novel in vivo model for the study of human immunodeficiency virus type 1 transcription inhibitors: evaluation of new 6-desfluoroquinolone derivatives.
Stevens M, Pollicita M, Pannecouque C, Verbeken E, Tabarrini O, Cecchetti V, Aquaro S, Perno CF, Fravolini A, De Clercq E, Schols D, Balzarini J. Stevens M, et al. Among authors: pannecouque c. Antimicrob Agents Chemother. 2007 Apr;51(4):1407-13. doi: 10.1128/AAC.01251-06. Epub 2007 Jan 22. Antimicrob Agents Chemother. 2007. PMID: 17242146 Free PMC article.
The phthalocyanine prototype derivative Alcian Blue is the first synthetic agent with selective anti-human immunodeficiency virus activity due to its gp120 glycan-binding potential.
François KO, Pannecouque C, Auwerx J, Lozano V, Pérez-Pérez MJ, Schols D, Balzarini J. François KO, et al. Among authors: pannecouque c. Antimicrob Agents Chemother. 2009 Nov;53(11):4852-9. doi: 10.1128/AAC.00811-09. Epub 2009 Aug 31. Antimicrob Agents Chemother. 2009. PMID: 19721061 Free PMC article.
Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase.
Cullen MD, Ho WC, Bauman JD, Das K, Arnold E, Hartman TL, Watson KM, Buckheit RW, Pannecouque C, De Clercq E, Cushman M. Cullen MD, et al. Among authors: pannecouque c. J Med Chem. 2009 Oct 22;52(20):6467-73. doi: 10.1021/jm901167t. J Med Chem. 2009. PMID: 19775161 Free PMC article.
454 results