Szyf M - Search Results

1

[¹¹C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease.

Pascoal TA, Chamoun M, Lax E, Wey HY, Shin M, Ng KP, Kang MS, Mathotaarachchi S, Benedet AL, Therriault J, Lussier FZ, Schroeder FA, DuBois JM, Hightower BG, Gilbert TM, Zürcher NR, Wang C, Hopewell R, Chakravarty M, Savard M, Thomas E, Mohaddes S, Farzin S, Salaciak A, Tullo S, Cuello AC, Soucy JP, Massarweh G, Hwang H, Kobayashi E, Hyman BT, Dickerson BC, Guiot MC, Szyf M, Gauthier S, Hooker JM, Rosa-Neto P. Pascoal TA, et al. Among authors: szyf m. Nat Commun. 2022 Jul 19;13(1):4171. doi: 10.1038/s41467-022-30653-5. Nat Commun. 2022. PMID: 35853847 Free PMC article.

2

Mitochondrial abnormalities in neuroectodermal cells stably expressing human amyloid precursor protein (hAPP751).

Grant SM, Shankar SL, Chalmers-Redman RM, Tatton WG, Szyf M, Cuello AC. Grant SM, et al. Among authors: szyf m. Neuroreport. 1999 Jan 18;10(1):41-6. doi: 10.1097/00001756-199901180-00008. Neuroreport. 1999. PMID: 10094130

3

Phosphorylation of mitogen-activated protein kinase is altered in neuroectodermal cells overexpressing the human amyloid precursor protein 751 isoform.

Grant SM, Morinville A, Maysinger D, Szyf M, Cuello AC. Grant SM, et al. Among authors: szyf m. Brain Res Mol Brain Res. 1999 Oct 1;72(2):115-20. doi: 10.1016/s0169-328x(99)00157-6. Brain Res Mol Brain Res. 1999. PMID: 10529469

4

Abeta immunoreactive material is present in several intracellular compartments in transfected, neuronally differentiated, P19 cells expressing the human amyloid beta-protein precursor.

Grant SM, Ducatenzeiler A, Szyf M, Cuello AC. Grant SM, et al. Among authors: szyf m. J Alzheimers Dis. 2000 Nov;2(3-4):207-22. doi: 10.3233/jad-2000-23-403. J Alzheimers Dis. 2000. PMID: 12214085

5

Rat transgenic models with a phenotype of intracellular Abeta accumulation in hippocampus and cortex.

Echeverria V, Ducatenzeiler A, Alhonen L, Janne J, Grant SM, Wandosell F, Muro A, Baralle F, Li H, Duff K, Szyf M, Cuello AC. Echeverria V, et al. Among authors: szyf m. J Alzheimers Dis. 2004 Jun;6(3):209-19. doi: 10.3233/jad-2004-6301. J Alzheimers Dis. 2004. PMID: 15201476

6

Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the beta-amyloid peptide intracellularly in hippocampal and cortical neurons.

Echeverria V, Ducatenzeiler A, Dowd E, Jänne J, Grant SM, Szyf M, Wandosell F, Avila J, Grimm H, Dunnett SB, Hartmann T, Alhonen L, Cuello AC. Echeverria V, et al. Among authors: szyf m. Neuroscience. 2004;129(3):583-92. doi: 10.1016/j.neuroscience.2004.07.036. Neuroscience. 2004. PMID: 15541880

7

Early dysregulation of hippocampal proteins in transgenic rats with Alzheimer's disease-linked mutations in amyloid precursor protein and presenilin 1.

Vercauteren FG, Clerens S, Roy L, Hamel N, Arckens L, Vandesande F, Alhonen L, Janne J, Szyf M, Cuello AC. Vercauteren FG, et al. Among authors: szyf m. Brain Res Mol Brain Res. 2004 Dec 20;132(2):241-59. doi: 10.1016/j.molbrainres.2004.10.012. Brain Res Mol Brain Res. 2004. PMID: 15582162

8

High intracellular concentrations of amyloid-beta block nuclear translocation of phosphorylated CREB.

Arvanitis DN, Ducatenzeiler A, Ou JN, Grodstein E, Andrews SD, Tendulkar SR, Ribeiro-da-Silva A, Szyf M, Cuello AC. Arvanitis DN, et al. Among authors: szyf m. J Neurochem. 2007 Oct;103(1):216-28. doi: 10.1111/j.1471-4159.2007.04704.x. Epub 2007 Jun 22. J Neurochem. 2007. PMID: 17587310 Free article.

9

A novel transgenic rat model with a full Alzheimer's-like amyloid pathology displays pre-plaque intracellular amyloid-beta-associated cognitive impairment.

Leon WC, Canneva F, Partridge V, Allard S, Ferretti MT, DeWilde A, Vercauteren F, Atifeh R, Ducatenzeiler A, Klein W, Szyf M, Alhonen L, Cuello AC. Leon WC, et al. Among authors: szyf m. J Alzheimers Dis. 2010;20(1):113-26. doi: 10.3233/JAD-2010-1349. J Alzheimers Dis. 2010. PMID: 20164597

10

Transgenic mice as a model of pre-clinical Alzheimer's disease.

Ferretti MT, Partridge V, Leon WC, Canneva F, Allard S, Arvanitis DN, Vercauteren F, Houle D, Ducatenzeiler A, Klein WL, Glabe CG, Szyf M, Cuello AC. Ferretti MT, et al. Among authors: szyf m. Curr Alzheimer Res. 2011 Feb;8(1):4-23. doi: 10.2174/156720511794604561. Curr Alzheimer Res. 2011. PMID: 21143159

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