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Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma.
Ferguson ID, Lin YT, Lam C, Shao H, Tharp KM, Hale M, Kasap C, Mariano MC, Kishishita A, Patiño Escobar B, Mandal K, Steri V, Wang D, Phojanakong P, Tuomivaara ST, Hann B, Driessen C, Van Ness B, Gestwicki JE, Wiita AP. Ferguson ID, et al. Among authors: hann b. Cell Chem Biol. 2022 Aug 18;29(8):1288-1302.e7. doi: 10.1016/j.chembiol.2022.06.010. Epub 2022 Jul 18. Cell Chem Biol. 2022. PMID: 35853457 Free PMC article.
Tumor detection by imaging proteolytic activity.
Darragh MR, Schneider EL, Lou J, Phojanakong PJ, Farady CJ, Marks JD, Hann BC, Craik CS. Darragh MR, et al. Cancer Res. 2010 Feb 15;70(4):1505-12. doi: 10.1158/0008-5472.CAN-09-1640. Epub 2010 Feb 9. Cancer Res. 2010. PMID: 20145119 Free PMC article.
Resiliency and vulnerability in the HER2-HER3 tumorigenic driver.
Amin DN, Sergina N, Ahuja D, McMahon M, Blair JA, Wang D, Hann B, Koch KM, Shokat KM, Moasser MM. Amin DN, et al. Among authors: hann b. Sci Transl Med. 2010 Jan 27;2(16):16ra7. doi: 10.1126/scitranslmed.3000389. Sci Transl Med. 2010. PMID: 20371474 Free PMC article.
A tumor-suppressing function in the epithelial adhesion protein Trask.
Spassov DS, Wong CH, Harris G, McDonough S, Phojanakong P, Wang D, Hann B, Bazarov AV, Yaswen P, Khanafshar E, Moasser MM. Spassov DS, et al. Among authors: hann b. Oncogene. 2012 Jan 26;31(4):419-31. doi: 10.1038/onc.2011.246. Epub 2011 Jun 27. Oncogene. 2012. PMID: 21706059 Free PMC article.
Oncogene mimicry as a mechanism of primary resistance to BRAF inhibitors.
Sos ML, Levin RS, Gordan JD, Oses-Prieto JA, Webber JT, Salt M, Hann B, Burlingame AL, McCormick F, Bandyopadhyay S, Shokat KM. Sos ML, et al. Among authors: hann b. Cell Rep. 2014 Aug 21;8(4):1037-48. doi: 10.1016/j.celrep.2014.07.010. Epub 2014 Aug 7. Cell Rep. 2014. PMID: 25127139 Free PMC article.
Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells.
Sherbenou DW, Aftab BT, Su Y, Behrens CR, Wiita A, Logan AC, Acosta-Alvear D, Hann BC, Walter P, Shuman MA, Wu X, Atkinson JP, Wolf JL, Martin TG, Liu B. Sherbenou DW, et al. Among authors: hann bc. J Clin Invest. 2016 Dec 1;126(12):4640-4653. doi: 10.1172/JCI85856. Epub 2016 Nov 14. J Clin Invest. 2016. PMID: 27841764 Free PMC article.
96 results