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Safety and efficacy of the 5-lipoxygenase-activating protein inhibitor AZD5718 in patients with recent myocardial infarction: The phase 2a FLAVOUR study.
Prescott E, Angerås O, Erlinge D, Grove EL, Hedman M, Jensen LO, Pernow J, Saraste A, Åkerblom A, Svedlund S, Rudvik A, Knöchel J, Lindstedt EL, Garkaviy P, Gan LM, Gabrielsen A. Prescott E, et al. Among authors: hedman m. Int J Cardiol. 2022 Oct 15;365:34-40. doi: 10.1016/j.ijcard.2022.07.016. Epub 2022 Jul 14. Int J Cardiol. 2022. PMID: 35842004 Free article. Clinical Trial.
Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up.
Hartikainen J, Hassinen I, Hedman A, Kivelä A, Saraste A, Knuuti J, Husso M, Mussalo H, Hedman M, Rissanen TT, Toivanen P, Heikura T, Witztum JL, Tsimikas S, Ylä-Herttuala S. Hartikainen J, et al. Among authors: hedman m, hedman a. Eur Heart J. 2017 Sep 1;38(33):2547-2555. doi: 10.1093/eurheartj/ehx352. Eur Heart J. 2017. PMID: 28903476 Free PMC article. Clinical Trial.
Synthetic mRNA Encoding VEGF-A in Patients Undergoing Coronary Artery Bypass Grafting: Design of a Phase 2a Clinical Trial.
Anttila V, Saraste A, Knuuti J, Jaakkola P, Hedman M, Svedlund S, Lagerström-Fermér M, Kjaer M, Jeppsson A, Gan LM. Anttila V, et al. Among authors: hedman m. Mol Ther Methods Clin Dev. 2020 Jun 1;18:464-472. doi: 10.1016/j.omtm.2020.05.030. eCollection 2020 Sep 11. Mol Ther Methods Clin Dev. 2020. PMID: 32728595 Free PMC article.
Design and rationale of FLAVOUR: A phase IIa efficacy study of the 5-lipoxygenase activating protein antagonist AZD5718 in patients with recent myocardial infarction.
Prescott E, Pernow J, Saraste A, Åkerblom A, Angerås O, Erlinge D, Grove EL, Hedman M, Jensen LO, Svedlund S, Kjaer M, Lagerström-Fermér M, Gan LM. Prescott E, et al. Among authors: hedman m. Contemp Clin Trials Commun. 2020 Jul 30;19:100629. doi: 10.1016/j.conctc.2020.100629. eCollection 2020 Sep. Contemp Clin Trials Commun. 2020. PMID: 32875138 Free PMC article.
Direct intramyocardial injection of VEGF mRNA in patients undergoing coronary artery bypass grafting.
Anttila V, Saraste A, Knuuti J, Hedman M, Jaakkola P, Laugwitz KL, Krane M, Jeppsson A, Sillanmäki S, Rosenmeier J, Zingmark P, Rudvik A, Garkaviy P, Watson C, Pangalos MN, Chien KR, Fritsche-Danielson R, Collén A, Gan LM. Anttila V, et al. Among authors: hedman m. Mol Ther. 2023 Mar 1;31(3):866-874. doi: 10.1016/j.ymthe.2022.11.017. Epub 2022 Dec 17. Mol Ther. 2023. PMID: 36528793 Free PMC article. Clinical Trial.
24-hour ambulatory blood pressure and cryptogenic ischemic stroke in young adults.
Tulkki L, Martinez-Majander N, Haapalahti P, Tolppanen H, Sinisalo J, Repo O, Sarkanen T, Numminen H, Ryödi E, Ylikotila P, Roine RO, Lautamäki R, Saraste A, Miettinen T, Autere J, Jäkälä P, Hedman M, Huhtakangas J, Junttola U, Putaala J, Pirinen J; SECRETO Study Group. Tulkki L, et al. Among authors: hedman m. Ann Med. 2023 Dec;55(1):2203513. doi: 10.1080/07853890.2023.2203513. Ann Med. 2023. PMID: 37086083 Free PMC article.
Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: phase II results of the Kuopio Angiogenesis Trial (KAT).
Hedman M, Hartikainen J, Syvänne M, Stjernvall J, Hedman A, Kivelä A, Vanninen E, Mussalo H, Kauppila E, Simula S, Närvänen O, Rantala A, Peuhkurinen K, Nieminen MS, Laakso M, Ylä-Herttuala S. Hedman M, et al. Among authors: hedman a. Circulation. 2003 Jun 3;107(21):2677-83. doi: 10.1161/01.CIR.0000070540.80780.92. Epub 2003 May 12. Circulation. 2003. PMID: 12742981 Clinical Trial.
149 results