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A human IgM enriched immunoglobulin preparation, Pentaglobin, reverses autoimmune diabetes without immune suppression in NOD mice.
Sci Rep. 2022 Jul 11;12(1):11731. doi: 10.1038/s41598-022-15676-8.
Sci Rep. 2022.
PMID: 35821261
Free PMC article.
Healthy Donor Polyclonal IgMs Diminish B-Lymphocyte Autoreactivity, Enhance Regulatory T-Cell Generation, and Reverse Type 1 Diabetes in NOD Mice.
Wilson CS, Chhabra P, Marshall AF, Morr CV, Stocks BT, Hoopes EM, Bonami RH, Poffenberger G, Brayman KL, Moore DJ.
Wilson CS, et al. Among authors: hoopes em.
Diabetes. 2018 Nov;67(11):2349-2360. doi: 10.2337/db18-0456. Epub 2018 Aug 21.
Diabetes. 2018.
PMID: 30131391
Free PMC article.
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B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib.
Wilson CS, Spaeth JM, Karp J, Stocks BT, Hoopes EM, Stein RW, Moore DJ.
Wilson CS, et al. Among authors: hoopes em.
JCI Insight. 2019 Apr 9;5(9):e125317. doi: 10.1172/jci.insight.125317.
JCI Insight. 2019.
PMID: 30964447
Free PMC article.
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Regulation of Diabetogenic Immunity by IL-15-Activated Regulatory CD8 T Cells in Type 1 Diabetes.
Stocks BT, Wilson CS, Marshall AF, Hoopes EM, Moore DJ.
Stocks BT, et al. Among authors: hoopes em.
J Immunol. 2019 Jul 1;203(1):158-166. doi: 10.4049/jimmunol.1800976. Epub 2019 May 24.
J Immunol. 2019.
PMID: 31127035
Free PMC article.
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Metabolic preconditioning in CD4+ T cells restores inducible immune tolerance in lupus-prone mice.
Wilson CS, Stocks BT, Hoopes EM, Rhoads JP, McNew KL, Major AS, Moore DJ.
Wilson CS, et al. Among authors: hoopes em.
JCI Insight. 2021 Oct 8;6(19):e143245. doi: 10.1172/jci.insight.143245.
JCI Insight. 2021.
PMID: 34403367
Free PMC article.
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