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Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity.
Nat Genet. 2022 Jul;54(7):996-1012. doi: 10.1038/s41588-022-01108-w. Epub 2022 Jul 11.
Nat Genet. 2022.
PMID: 35817971
Free PMC article.
Phase II Clinical Trial of Pembrolizumab and Chemotherapy Reveals Distinct Transcriptomic Profiles by Radiologic Response in Metastatic Triple-Negative Breast Cancer.
Wilkerson AD, Parthasarathy PB, Stabellini N, Mitchell C, Pavicic PG Jr, Fu P, Rupani A, Husic H, Rayman PA, Swaidani S, Abraham J, Budd GT, Moore H, Al-Hilli Z, Ko JS, Baar J, Chan TA, Alban T, Diaz-Montero CM, Montero AJ.
Wilkerson AD, et al. Among authors: parthasarathy pb.
Clin Cancer Res. 2024 Jan 5;30(1):82-93. doi: 10.1158/1078-0432.CCR-23-1349.
Clin Cancer Res. 2024.
PMID: 37882661
Free PMC article.
Clinical Trial.
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VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms.
Zhang K, Zakeri A, Alban T, Dong J, Ta HM, Zalavadia AH, Branicky A, Zhao H, Juric I, Husich H, Parthasarathy PB, Rupani A, Drazba JA, Chakraborty AA, Ching-Cheng Huang S, Chan T, Avril S, Wang LL.
Zhang K, et al. Among authors: parthasarathy pb.
Cell Rep. 2024 Jan 23;43(1):113661. doi: 10.1016/j.celrep.2023.113661. Epub 2024 Jan 3.
Cell Rep. 2024.
PMID: 38175754
Free PMC article.
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Unsupervised and supervised AI on molecular dynamics simulations reveals complex characteristics of HLA-A2-peptide immunogenicity.
Weber JK, Morrone JA, Kang SG, Zhang L, Lang L, Chowell D, Krishna C, Huynh T, Parthasarathy P, Luan B, Alban TJ, Cornell WD, Chan TA.
Weber JK, et al.
Brief Bioinform. 2023 Nov 22;25(1):bbad504. doi: 10.1093/bib/bbad504.
Brief Bioinform. 2023.
PMID: 38233090
Free PMC article.
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LRIG1 engages ligand VISTA and impairs tumor-specific CD8+ T cell responses.
Ta HM, Roy D, Zhang K, Alban T, Juric I, Dong J, Parthasarathy PB, Patnaik S, Delaney E, Gilmour C, Zakeri A, Shukla N, Rupani A, Phoon YP, Liu C, Avril S, Gastman B, Chan T, Wang LL.
Ta HM, et al. Among authors: parthasarathy pb.
Sci Immunol. 2024 May 17;9(95):eadi7418. doi: 10.1126/sciimmunol.adi7418. Epub 2024 May 17.
Sci Immunol. 2024.
PMID: 38758807
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