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Structure-specific amyloid precipitation in biofluids.
Rodrigues M, Bhattacharjee P, Brinkmalm A, Do DT, Pearson CM, De S, Ponjavic A, Varela JA, Kulenkampff K, Baudrexel I, Emin D, Ruggeri FS, Lee JE, Carr AR, Knowles TPJ, Zetterberg H, Snaddon TN, Gandhi S, Lee SF, Klenerman D. Rodrigues M, et al. Among authors: klenerman d. Nat Chem. 2022 Sep;14(9):1045-1053. doi: 10.1038/s41557-022-00976-3. Epub 2022 Jul 7. Nat Chem. 2022. PMID: 35798951 Free article.
Lipid peroxidation is essential for α-synuclein-induced cell death.
Angelova PR, Horrocks MH, Klenerman D, Gandhi S, Abramov AY, Shchepinov MS. Angelova PR, et al. Among authors: klenerman d. J Neurochem. 2015 May;133(4):582-9. doi: 10.1111/jnc.13024. Epub 2015 Mar 1. J Neurochem. 2015. PMID: 25580849 Free PMC article.
Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids.
Horrocks MH, Lee SF, Gandhi S, Magdalinou NK, Chen SW, Devine MJ, Tosatto L, Kjaergaard M, Beckwith JS, Zetterberg H, Iljina M, Cremades N, Dobson CM, Wood NW, Klenerman D. Horrocks MH, et al. Among authors: klenerman d. ACS Chem Neurosci. 2016 Mar 16;7(3):399-406. doi: 10.1021/acschemneuro.5b00324. Epub 2016 Feb 4. ACS Chem Neurosci. 2016. PMID: 26800462 Free PMC article.
Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading.
Iljina M, Garcia GA, Horrocks MH, Tosatto L, Choi ML, Ganzinger KA, Abramov AY, Gandhi S, Wood NW, Cremades N, Dobson CM, Knowles TP, Klenerman D. Iljina M, et al. Among authors: klenerman d. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1206-15. doi: 10.1073/pnas.1524128113. Epub 2016 Feb 16. Proc Natl Acad Sci U S A. 2016. PMID: 26884195 Free PMC article.
261 results