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Anti-Extra Domain B Splice Variant of Fibronectin Antibody-Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade.
Mol Cancer Ther. 2022 Sep 6;21(9):1462-1472. doi: 10.1158/1535-7163.MCT-22-0099.
Mol Cancer Ther. 2022.
PMID: 35793468
Free PMC article.
PF-06804103, A Site-specific Anti-HER2 Antibody-Drug Conjugate for the Treatment of HER2-expressing Breast, Gastric, and Lung Cancers.
Graziani EI, Sung M, Ma D, Narayanan B, Marquette K, Puthenveetil S, Tumey LN, Bikker J, Casavant J, Bennett EM, Charati MB, Golas J, Hosselet C, Rohde CM, Hu G, Guffroy M, Falahatpisheh H, Finkelstein M, Clark T, Barletta F, Tchistiakova L, Lucas J, Rosfjord E, Loganzo F, O'Donnell CJ, Gerber HP, Sapra P.
Graziani EI, et al. Among authors: falahatpisheh h.
Mol Cancer Ther. 2020 Oct;19(10):2068-2078. doi: 10.1158/1535-7163.MCT-20-0237. Epub 2020 Aug 3.
Mol Cancer Ther. 2020.
PMID: 32747418
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Anti-EFNA4 Calicheamicin Conjugates Effectively Target Triple-Negative Breast and Ovarian Tumor-Initiating Cells to Result in Sustained Tumor Regressions.
Damelin M, Bankovich A, Park A, Aguilar J, Anderson W, Santaguida M, Aujay M, Fong S, Khandke K, Pulito V, Ernstoff E, Escarpe P, Bernstein J, Pysz M, Zhong W, Upeslacis E, Lucas J, Lucas J, Nichols T, Loving K, Foord O, Hampl J, Stull R, Barletta F, Falahatpisheh H, Sapra P, Gerber HP, Dylla SJ.
Damelin M, et al. Among authors: falahatpisheh h.
Clin Cancer Res. 2015 Sep 15;21(18):4165-73. doi: 10.1158/1078-0432.CCR-15-0695. Epub 2015 May 26.
Clin Cancer Res. 2015.
PMID: 26015513
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A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions.
Damelin M, Bankovich A, Bernstein J, Lucas J, Chen L, Williams S, Park A, Aguilar J, Ernstoff E, Charati M, Dushin R, Aujay M, Lee C, Ramoth H, Milton M, Hampl J, Lazetic S, Pulito V, Rosfjord E, Sun Y, King L, Barletta F, Betts A, Guffroy M, Falahatpisheh H, O'Donnell CJ, Stull R, Pysz M, Escarpe P, Liu D, Foord O, Gerber HP, Sapra P, Dylla SJ.
Damelin M, et al. Among authors: falahatpisheh h.
Sci Transl Med. 2017 Jan 11;9(372):eaag2611. doi: 10.1126/scitranslmed.aag2611.
Sci Transl Med. 2017.
PMID: 28077676
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Liver Microvascular Injury and Thrombocytopenia of Antibody-Calicheamicin Conjugates in Cynomolgus Monkeys-Mechanism and Monitoring.
Guffroy M, Falahatpisheh H, Biddle K, Kreeger J, Obert L, Walters K, Goldstein R, Boucher G, Coskran T, Reagan W, Sullivan D, Huang C, Sokolowski S, Giovanelli R, Gerber HP, Finkelstein M, Khan N.
Guffroy M, et al. Among authors: falahatpisheh h.
Clin Cancer Res. 2017 Apr 1;23(7):1760-1770. doi: 10.1158/1078-0432.CCR-16-0939. Epub 2016 Sep 28.
Clin Cancer Res. 2017.
PMID: 27683177
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Antibody-drug conjugates as targeted therapies: Are we there yet? A critical review of the current clinical landscape.
Tarcsa E, Guffroy MR, Falahatpisheh H, Phipps C, Kalvass JC.
Tarcsa E, et al. Among authors: falahatpisheh h.
Drug Discov Today Technol. 2020 Dec;37:13-22. doi: 10.1016/j.ddtec.2020.07.002. Epub 2020 Sep 29.
Drug Discov Today Technol. 2020.
PMID: 34895651
Review.
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Anatomic and Clinical Pathology Characterization of Drug-Induced Sinusoidal Obstruction Syndrome (Veno-Occlusive Disease) in Cynomolgus Macaques.
Kohnken R, Falahatpisheh H, Janardhan KS, Guffroy M.
Kohnken R, et al. Among authors: falahatpisheh h.
Toxicol Pathol. 2022 Jan;50(1):13-22. doi: 10.1177/01926233211037932. Epub 2021 Aug 20.
Toxicol Pathol. 2022.
PMID: 34414838
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Activation profiles of HSPA5 during the glomerular mesangial cell stress response to chemical injury.
Falahatpisheh H, Nanez A, Montoya-Durango D, Qian Y, Tiffany-Castiglioni E, Ramos KS.
Falahatpisheh H, et al.
Cell Stress Chaperones. 2007 Autumn;12(3):209-18. doi: 10.1379/csc-259.1.
Cell Stress Chaperones. 2007.
PMID: 17915553
Free PMC article.
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