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Piezo proteins are pore-forming subunits of mechanically activated channels.
Coste B, Xiao B, Santos JS, Syeda R, Grandl J, Spencer KS, Kim SE, Schmidt M, Mathur J, Dubin AE, Montal M, Patapoutian A. Coste B, et al. Among authors: patapoutian a. Nature. 2012 Feb 19;483(7388):176-81. doi: 10.1038/nature10812. Nature. 2012. PMID: 22343900 Free PMC article.
Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels.
Albuisson J, Murthy SE, Bandell M, Coste B, Louis-Dit-Picard H, Mathur J, Fénéant-Thibault M, Tertian G, de Jaureguiberry JP, Syfuss PY, Cahalan S, Garçon L, Toutain F, Simon Rohrlich P, Delaunay J, Picard V, Jeunemaitre X, Patapoutian A. Albuisson J, et al. Among authors: patapoutian a. Nat Commun. 2013;4:1884. doi: 10.1038/ncomms2899. Nat Commun. 2013. PMID: 23695678 Free PMC article.
Piezo1, a mechanically activated ion channel, is required for vascular development in mice.
Ranade SS, Qiu Z, Woo SH, Hur SS, Murthy SE, Cahalan SM, Xu J, Mathur J, Bandell M, Coste B, Li YS, Chien S, Patapoutian A. Ranade SS, et al. Among authors: patapoutian a. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10347-52. doi: 10.1073/pnas.1409233111. Epub 2014 Jun 23. Proc Natl Acad Sci U S A. 2014. PMID: 24958852 Free PMC article.
Piezo1 Channels Are Inherently Mechanosensitive.
Syeda R, Florendo MN, Cox CD, Kefauver JM, Santos JS, Martinac B, Patapoutian A. Syeda R, et al. Among authors: patapoutian a. Cell Rep. 2016 Nov 8;17(7):1739-1746. doi: 10.1016/j.celrep.2016.10.033. Cell Rep. 2016. PMID: 27829145 Free PMC article.
121 results