Barzel A - Search Results

1

Frequent aneuploidy in primary human T cells after CRISPR-Cas9 cleavage.

Nahmad AD, Reuveni E, Goldschmidt E, Tenne T, Liberman M, Horovitz-Fried M, Khosravi R, Kobo H, Reinstein E, Madi A, Ben-David U, Barzel A. Nahmad AD, et al. Among authors: barzel a. Nat Biotechnol. 2022 Dec;40(12):1807-1813. doi: 10.1038/s41587-022-01377-0. Epub 2022 Jun 30. Nat Biotechnol. 2022. PMID: 35773341 Free PMC article.

2

In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice.

Nahmad AD, Lazzarotto CR, Zelikson N, Kustin T, Tenuta M, Huang D, Reuveni I, Nataf D, Raviv Y, Horovitz-Fried M, Dotan I, Carmi Y, Rosin-Arbesfeld R, Nemazee D, Voss JE, Stern A, Tsai SQ, Barzel A. Nahmad AD, et al. Among authors: barzel a. Nat Biotechnol. 2022 Aug;40(8):1241-1249. doi: 10.1038/s41587-022-01328-9. Epub 2022 Jun 9. Nat Biotechnol. 2022. PMID: 35681059 Free PMC article.

3

Engineered B cells expressing an anti-HIV antibody enable memory retention, isotype switching and clonal expansion.

Nahmad AD, Raviv Y, Horovitz-Fried M, Sofer I, Akriv T, Nataf D, Dotan I, Carmi Y, Burstein D, Wine Y, Benhar I, Barzel A. Nahmad AD, et al. Among authors: barzel a. Nat Commun. 2020 Nov 17;11(1):5851. doi: 10.1038/s41467-020-19649-1. Nat Commun. 2020. PMID: 33203857 Free PMC article.

4

MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression.

Pozzi S, Scomparin A, Ben-Shushan D, Yeini E, Ofek P, Nahmad AD, Soffer S, Ionescu A, Ruggiero A, Barzel A, Brem H, Hyde TM, Barshack I, Sinha S, Ruppin E, Weiss T, Madi A, Perlson E, Slutsky I, Florindo HF, Satchi-Fainaro R. Pozzi S, et al. Among authors: barzel a. JCI Insight. 2022 Sep 8;7(17):e154804. doi: 10.1172/jci.insight.154804. JCI Insight. 2022. PMID: 35980743 Free PMC article.

5

Finding a match: how do homologous sequences get together for recombination?

Barzel A, Kupiec M. Barzel A, et al. Nat Rev Genet. 2008 Jan;9(1):27-37. doi: 10.1038/nrg2224. Nat Rev Genet. 2008. PMID: 18040271 Review.

6

Promoterless gene targeting without nucleases ameliorates haemophilia B in mice.

Barzel A, Paulk NK, Shi Y, Huang Y, Chu K, Zhang F, Valdmanis PN, Spector LP, Porteus MH, Gaensler KM, Kay MA. Barzel A, et al. Nature. 2015 Jan 15;517(7534):360-4. doi: 10.1038/nature13864. Epub 2014 Oct 29. Nature. 2015. PMID: 25363772 Free PMC article.

7

Promoterless Gene Targeting Approach Combined to CRISPR/Cas9 Efficiently Corrects Hemophilia B Phenotype in Neonatal Mice.

Lisjak M, De Caneva A, Marais T, Barbon E, Biferi MG, Porro F, Barzel A, Zentilin L, Kay MA, Mingozzi F, Muro AF. Lisjak M, et al. Among authors: barzel a. Front Genome Ed. 2022 Mar 11;4:785698. doi: 10.3389/fgeed.2022.785698. eCollection 2022. Front Genome Ed. 2022. PMID: 35359664 Free PMC article.

8

Antibody Repertoire Analysis of Tumor-Infiltrating B Cells Reveals Distinct Signatures and Distributions Across Tissues.

Aizik L, Dror Y, Taussig D, Barzel A, Carmi Y, Wine Y. Aizik L, et al. Among authors: barzel a. Front Immunol. 2021 Jul 19;12:705381. doi: 10.3389/fimmu.2021.705381. eCollection 2021. Front Immunol. 2021. PMID: 34349765 Free PMC article.

9

Native homing endonucleases can target conserved genes in humans and in animal models.

Barzel A, Privman E, Peeri M, Naor A, Shachar E, Burstein D, Lazary R, Gophna U, Pupko T, Kupiec M. Barzel A, et al. Nucleic Acids Res. 2011 Aug;39(15):6646-59. doi: 10.1093/nar/gkr242. Epub 2011 Apr 27. Nucleic Acids Res. 2011. PMID: 21525128 Free PMC article.

10

Coupling AAV-mediated promoterless gene targeting to SaCas9 nuclease to efficiently correct liver metabolic diseases.

De Caneva A, Porro F, Bortolussi G, Sola R, Lisjak M, Barzel A, Giacca M, Kay MA, Vlahoviček K, Zentilin L, Muro AF. De Caneva A, et al. Among authors: barzel a. JCI Insight. 2019 Jun 18;5(15):e128863. doi: 10.1172/jci.insight.128863. JCI Insight. 2019. PMID: 31211694 Free PMC article.

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