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Hepatic Mitochondrial Dysfunction and Risk of Liver Disease in an Ovine Model of "PCOS Males".
Biomedicines. 2022 May 31;10(6):1291. doi: 10.3390/biomedicines10061291.
Biomedicines. 2022.
PMID: 35740312
Free PMC article.
Aberrant subcutaneous adipogenesis precedes adult metabolic dysfunction in an ovine model of polycystic ovary syndrome (PCOS).
Siemienowicz KJ, Coukan F, Franks S, Rae MT, Duncan WC.
Siemienowicz KJ, et al.
Mol Cell Endocrinol. 2021 Jan 1;519:111042. doi: 10.1016/j.mce.2020.111042. Epub 2020 Oct 1.
Mol Cell Endocrinol. 2021.
PMID: 33010309
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Pubertal FGF21 deficit is central in the metabolic pathophysiology of an ovine model of polycystic ovary syndrome.
Siemienowicz KJ, Furmanska K, Filis P, Talia C, Thomas J, Fowler PA, Rae MT, Duncan WC.
Siemienowicz KJ, et al.
Mol Cell Endocrinol. 2021 Apr 5;525:111196. doi: 10.1016/j.mce.2021.111196. Epub 2021 Feb 6.
Mol Cell Endocrinol. 2021.
PMID: 33556473
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Fetal androgen exposure is a determinant of adult male metabolic health.
Siemienowicz KJ, Filis P, Shaw S, Douglas A, Thomas J, Mulroy S, Howie F, Fowler PA, Duncan WC, Rae MT.
Siemienowicz KJ, et al.
Sci Rep. 2019 Dec 27;9(1):20195. doi: 10.1038/s41598-019-56790-4.
Sci Rep. 2019.
PMID: 31882954
Free PMC article.
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Early pregnancy maternal progesterone administration alters pituitary and testis function and steroid profile in male fetuses.
Siemienowicz KJ, Wang Y, Marečková M, Nio-Kobayashi J, Fowler PA, Rae MT, Duncan WC.
Siemienowicz KJ, et al.
Sci Rep. 2020 Dec 14;10(1):21920. doi: 10.1038/s41598-020-78976-x.
Sci Rep. 2020.
PMID: 33318609
Free PMC article.
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Developmental programming of polycystic ovary syndrome (PCOS): prenatal androgens establish pancreatic islet α/β cell ratio and subsequent insulin secretion.
Ramaswamy S, Grace C, Mattei AA, Siemienowicz K, Brownlee W, MacCallum J, McNeilly AS, Duncan WC, Rae MT.
Ramaswamy S, et al.
Sci Rep. 2016 Jun 6;6:27408. doi: 10.1038/srep27408.
Sci Rep. 2016.
PMID: 27265420
Free PMC article.
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Insights into Manipulating Postprandial Energy Expenditure to Manage Weight Gain in Polycystic Ovary Syndrome.
Siemienowicz K, Rae MT, Howells F, Anderson C, Nicol LM, Franks S, Duncan WC.
Siemienowicz K, et al.
iScience. 2020 Jun 26;23(6):101164. doi: 10.1016/j.isci.2020.101164. Epub 2020 May 15.
iScience. 2020.
PMID: 32464593
Free PMC article.
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