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Macrophage PD-1 associates with neutrophilia and reduced bacterial killing in early cystic fibrosis airway disease.
Margaroli C, Horati H, Garratt LW, Giacalone VD, Schofield C, Dittrich AS, Rosenow T, Dobosh BS, Lim HS, Frey DL, Veltman M, Silva GL, Brown MR, Schultz C, Tiddens HAWM, Ranganathan S, Chandler JD, Qiu P, Peng L, Scholte BJ, Mall MA, Kicic A, Guglani L, Stick SM, Janssens HM, Tirouvanziam R. Margaroli C, et al. Among authors: schofield c. J Cyst Fibros. 2022 Nov;21(6):967-976. doi: 10.1016/j.jcf.2022.06.001. Epub 2022 Jun 19. J Cyst Fibros. 2022. PMID: 35732550 Free article.
Pseudomonas aeruginosa modulates neutrophil granule exocytosis in an in vitro model of airway infection.
Laucirica DR, Schofield CJ, McLean SA, Margaroli C, Agudelo-Romero P, Stick SM, Tirouvanziam R, Kicic A, Garratt LW; Western Australian Epithelial Research Program (WAERP); Australian Respiratory Early Surveillance Team for CF (AREST CF). Laucirica DR, et al. Among authors: schofield cj. Immunol Cell Biol. 2022 May;100(5):352-370. doi: 10.1111/imcb.12547. Epub 2022 Apr 11. Immunol Cell Biol. 2022. PMID: 35318736 Free PMC article.
Airway macrophages display decreased expression of receptors mediating and regulating scavenging in early cystic fibrosis lung disease.
Slimmen LJM, Giacalone VD, Schofield C, Horati H, Manaï BHAN, Estevão SC, Garratt LW, Peng L, Tirouvanziam R, Janssens HM, Unger WWJ. Slimmen LJM, et al. Among authors: schofield c. Front Immunol. 2023 Jun 29;14:1202009. doi: 10.3389/fimmu.2023.1202009. eCollection 2023. Front Immunol. 2023. PMID: 37457715 Free PMC article.
Cell-active small molecule inhibitors validate the SNM1A DNA repair nuclease as a cancer target.
Bielinski M, Henderson LR, Yosaatmadja Y, Swift LP, Baddock HT, Bowen MJ, Brem J, Jones PS, McElroy SP, Morrison A, Speake M, van Boeckel S, van Doornmalen E, van Groningen J, van den Hurk H, Gileadi O, Newman JA, McHugh PJ, Schofield CJ. Bielinski M, et al. Among authors: schofield cj. Chem Sci. 2024 Apr 30;15(21):8227-8241. doi: 10.1039/d4sc00367e. eCollection 2024 May 29. Chem Sci. 2024. PMID: 38817593 Free PMC article.
994 results