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Page 1
Large scale clinical trials: lessons from the COVID-19 pandemic.
Horsley AR, Pearmain L, Knight S, Schindler N, Wang R, Bennett M, Robey RC, Davies JC, Djukanović R, Heaney LG, Hussell T, Marciniak SJ, McGarvey LP, Porter J, Wilkinson T, Brightling C, Ho LP. Horsley AR, et al. Among authors: ho lp. BMJ Open Respir Res. 2022 Jun;9(1):e001226. doi: 10.1136/bmjresp-2022-001226. BMJ Open Respir Res. 2022. PMID: 35701071 Free PMC article.
Readily accessible CT scoring method to quantify fibrosis in IPF.
Fraser E, St Noble V, Hoyles RK, Benamore R, Ho LP. Fraser E, et al. Among authors: ho lp. BMJ Open Respir Res. 2020 Jun;7(1):e000584. doi: 10.1136/bmjresp-2020-000584. BMJ Open Respir Res. 2020. PMID: 32527873 Free PMC article.
ACCORD: A Multicentre, Seamless, Phase 2 Adaptive Randomisation Platform Study to Assess the Efficacy and Safety of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalised Patients: A structured summary of a study protocol for a randomised controlled trial.
Wilkinson T, Dixon R, Page C, Carroll M, Griffiths G, Ho LP, De Soyza A, Felton T, Lewis KE, Phekoo K, Chalmers JD, Gordon A, McGarvey L, Doherty J, Read RC, Shankar-Hari M, Martinez-Alier N, O'Kelly M, Duncan G, Walles R, Sykes J, Summers C, Singh D; ACCORD Collaborators. Wilkinson T, et al. Among authors: ho lp. Trials. 2020 Jul 31;21(1):691. doi: 10.1186/s13063-020-04584-9. Trials. 2020. PMID: 32736596 Free PMC article.
Successful awake proning is associated with improved clinical outcomes in patients with COVID-19: single-centre high-dependency unit experience.
Hallifax RJ, Porter BM, Elder PJ, Evans SB, Turnbull CD, Hynes G, Lardner R, Archer K, Bettinson HV, Nickol AH, Flight WG, Chapman SJ, Hardinge M, Hoyles RK, Saunders P, Sykes A, Wrightson JM, Moore A, Ho LP, Fraser E, Pavord ID, Talbot NP, Bafadhel M, Petousi N, Rahman NM; Oxford Respiratory Group. Hallifax RJ, et al. Among authors: ho lp. BMJ Open Respir Res. 2020 Sep;7(1):e000678. doi: 10.1136/bmjresp-2020-000678. BMJ Open Respir Res. 2020. PMID: 32928787 Free PMC article.
Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19.
Mann ER, Menon M, Knight SB, Konkel JE, Jagger C, Shaw TN, Krishnan S, Rattray M, Ustianowski A, Bakerly ND, Dark P, Lord G, Simpson A, Felton T, Ho LP; NIHR Respiratory TRC,; Feldmann M; CIRCO,; Grainger JR, Hussell T. Mann ER, et al. Among authors: ho lp. Sci Immunol. 2020 Sep 17;5(51):eabd6197. doi: 10.1126/sciimmunol.abd6197. Sci Immunol. 2020. PMID: 32943497 Free PMC article.
Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial.
Monk PD, Marsden RJ, Tear VJ, Brookes J, Batten TN, Mankowski M, Gabbay FJ, Davies DE, Holgate ST, Ho LP, Clark T, Djukanovic R, Wilkinson TMA; Inhaled Interferon Beta COVID-19 Study Group. Monk PD, et al. Among authors: ho lp. Lancet Respir Med. 2021 Feb;9(2):196-206. doi: 10.1016/S2213-2600(20)30511-7. Epub 2020 Nov 12. Lancet Respir Med. 2021. PMID: 33189161 Free PMC article. Clinical Trial.
Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID).
Wild JM, Porter JC, Molyneaux PL, George PM, Stewart I, Allen RJ, Aul R, Baillie JK, Barratt SL, Beirne P, Bianchi SM, Blaikley JF, Brooke J, Chaudhuri N, Collier G, Denneny EK, Docherty A, Fabbri L, Gibbons MA, Gleeson FV, Gooptu B, Hall IP, Hanley NA, Heightman M, Hillman TE, Johnson SR, Jones MG, Khan F, Lawson R, Mehta P, Mitchell JA, Platé M, Poinasamy K, Quint JK, Rivera-Ortega P, Semple M, Simpson AJ, Smith D, Spears M, Spencer LG, Stanel SC, Thickett DR, Thompson AAR, Walsh SL, Weatherley ND, Weeks ME, Wootton DG, Brightling CE, Chambers RC, Ho LP, Jacob J, Piper Hanley K, Wain LV, Jenkins RG. Wild JM, et al. Among authors: ho lp. BMJ Open Respir Res. 2021 Sep;8(1):e001049. doi: 10.1136/bmjresp-2021-001049. BMJ Open Respir Res. 2021. PMID: 34556492 Free PMC article.
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.
Evans RA, McAuley H, Harrison EM, Shikotra A, Singapuri A, Sereno M, Elneima O, Docherty AB, Lone NI, Leavy OC, Daines L, Baillie JK, Brown JS, Chalder T, De Soyza A, Diar Bakerly N, Easom N, Geddes JR, Greening NJ, Hart N, Heaney LG, Heller S, Howard L, Hurst JR, Jacob J, Jenkins RG, Jolley C, Kerr S, Kon OM, Lewis K, Lord JM, McCann GP, Neubauer S, Openshaw PJM, Parekh D, Pfeffer P, Rahman NM, Raman B, Richardson M, Rowland M, Semple MG, Shah AM, Singh SJ, Sheikh A, Thomas D, Toshner M, Chalmers JD, Ho LP, Horsley A, Marks M, Poinasamy K, Wain LV, Brightling CE; PHOSP-COVID Collaborative Group. Evans RA, et al. Among authors: ho lp. Lancet Respir Med. 2021 Nov;9(11):1275-1287. doi: 10.1016/S2213-2600(21)00383-0. Epub 2021 Oct 7. Lancet Respir Med. 2021. PMID: 34627560 Free PMC article.
Namilumab or infliximab compared with standard of care in hospitalised patients with COVID-19 (CATALYST): a randomised, multicentre, multi-arm, multistage, open-label, adaptive, phase 2, proof-of-concept trial.
Fisher BA, Veenith T, Slade D, Gaskell C, Rowland M, Whitehouse T, Scriven J, Parekh D, Balasubramaniam MS, Cooke G, Morley N, Gabriel Z, Wise MP, Porter J, McShane H, Ho LP, Newsome PN, Rowe A, Sharpe R, Thickett DR, Bion J, Gates S, Richards D, Kearns P; CATALYST investigators. Fisher BA, et al. Among authors: ho lp. Lancet Respir Med. 2022 Mar;10(3):255-266. doi: 10.1016/S2213-2600(21)00460-4. Epub 2021 Dec 16. Lancet Respir Med. 2022. PMID: 34922649 Free PMC article. Clinical Trial.
165 results