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Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.
Wang J, Thingholm LB, Skiecevičienė J, Rausch P, Kummen M, Hov JR, Degenhardt F, Heinsen FA, Rühlemann MC, Szymczak S, Holm K, Esko T, Sun J, Pricop-Jeckstadt M, Al-Dury S, Bohov P, Bethune J, Sommer F, Ellinghaus D, Berge RK, Hübenthal M, Koch M, Schwarz K, Rimbach G, Hübbe P, Pan WH, Sheibani-Tezerji R, Häsler R, Rosenstiel P, D'Amato M, Cloppenborg-Schmidt K, Künzel S, Laudes M, Marschall HU, Lieb W, Nöthlings U, Karlsen TH, Baines JF, Franke A. Wang J, et al. Among authors: franke a. Nat Genet. 2016 Nov;48(11):1396-1406. doi: 10.1038/ng.3695. Epub 2016 Oct 10. Nat Genet. 2016. PMID: 27723756 Free PMC article.
Beneficial Effects of a Dietary Weight Loss Intervention on Human Gut Microbiome Diversity and Metabolism Are Not Sustained during Weight Maintenance.
Heinsen FA, Fangmann D, Müller N, Schulte DM, Rühlemann MC, Türk K, Settgast U, Lieb W, Baines JF, Schreiber S, Franke A, Laudes M. Heinsen FA, et al. Among authors: franke a. Obes Facts. 2016;9(6):379-391. doi: 10.1159/000449506. Epub 2016 Nov 30. Obes Facts. 2016. PMID: 27898428 Free PMC article. Clinical Trial.
A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis.
Munz M, Willenborg C, Richter GM, Jockel-Schneider Y, Graetz C, Staufenbiel I, Wellmann J, Berger K, Krone B, Hoffmann P, van der Velde N, Uitterlinden AG, de Groot LCPGM, Sawalha AH, Direskeneli H, Saruhan-Direskeneli G, Guzeldemir-Akcakanat E, Keceli HG, Laudes M, Noack B, Teumer A, Holtfreter B, Kocher T, Eickholz P, Meyle J, Doerfer C, Bruckmann C, Lieb W, Franke A, Schreiber S, Nohutcu RM, Erdmann J, Loos BG, Jepsen S, Dommisch H, Schaefer AS. Munz M, et al. Among authors: franke a. Hum Mol Genet. 2017 Jul 1;26(13):2577-2588. doi: 10.1093/hmg/ddx151. Hum Mol Genet. 2017. PMID: 28449029
A haplotype block downstream of plasminogen is associated with chronic and aggressive periodontitis.
Munz M, Chen H, Jockel-Schneider Y, Adam K, Hoffman P, Berger K, Kocher T, Meyle J, Eickholz P, Doerfer C, Laudes M, Uitterlinden A, Lieb W, Franke A, Schreiber S, Offenbacher S, Divaris K, Bruckmann C, Loos BG, Jepsen S, Dommisch H, Schäefer AS. Munz M, et al. Among authors: franke a. J Clin Periodontol. 2017 Oct;44(10):962-970. doi: 10.1111/jcpe.12749. Epub 2017 Sep 11. J Clin Periodontol. 2017. PMID: 28548211
Hypothalamic Inflammation in Human Obesity Is Mediated by Environmental and Genetic Factors.
Kreutzer C, Peters S, Schulte DM, Fangmann D, Türk K, Wolff S, van Eimeren T, Ahrens M, Beckmann J, Schafmayer C, Becker T, Kerby T, Rohr A, Riedel C, Heinsen FA, Degenhardt F, Franke A, Rosenstiel P, Zubek N, Henning C, Freitag-Wolf S, Dempfle A, Psilopanagioti A, Petrou-Papadaki H, Lenk L, Jansen O, Schreiber S, Laudes M. Kreutzer C, et al. Among authors: franke a. Diabetes. 2017 Sep;66(9):2407-2415. doi: 10.2337/db17-0067. Epub 2017 Jun 2. Diabetes. 2017. PMID: 28576837
Microbiomarkers in inflammatory bowel diseases: caveats come with caviar.
Sommer F, Rühlemann MC, Bang C, Höppner M, Rehman A, Kaleta C, Schmitt-Kopplin P, Dempfle A, Weidinger S, Ellinghaus E, Krauss-Etschmann S, Schmidt-Arras D, Aden K, Schulte D, Ellinghaus D, Schreiber S, Tholey A, Rupp J, Laudes M, Baines JF, Rosenstiel P, Franke A. Sommer F, et al. Among authors: franke a. Gut. 2017 Oct;66(10):1734-1738. doi: 10.1136/gutjnl-2016-313678. Epub 2017 Jul 21. Gut. 2017. PMID: 28733278 Free PMC article. No abstract available.
Application of the distance-based F test in an mGWAS investigating β diversity of intestinal microbiota identifies variants in SLC9A8 (NHE8) and 3 other loci.
Rühlemann MC, Degenhardt F, Thingholm LB, Wang J, Skiecevičienė J, Rausch P, Hov JR, Lieb W, Karlsen TH, Laudes M, Baines JF, Heinsen FA, Franke A. Rühlemann MC, et al. Among authors: franke a. Gut Microbes. 2018 Jan 2;9(1):68-75. doi: 10.1080/19490976.2017.1356979. Epub 2017 Aug 28. Gut Microbes. 2018. PMID: 28816579 Free PMC article.
Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans.
Fangmann D, Theismann EM, Türk K, Schulte DM, Relling I, Hartmann K, Keppler JK, Knipp JR, Rehman A, Heinsen FA, Franke A, Lenk L, Freitag-Wolf S, Appel E, Gorb S, Brenner C, Seegert D, Waetzig GH, Rosenstiel P, Schreiber S, Schwarz K, Laudes M. Fangmann D, et al. Among authors: franke a. Diabetes Care. 2018 Mar;41(3):398-405. doi: 10.2337/dc17-1967. Epub 2017 Dec 6. Diabetes Care. 2018. PMID: 29212824
1,703 results