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Inhibition of Adipose Tissue Beiging by HIV Integrase Inhibitors, Dolutegravir and Bictegravir, Is Associated with Adipocyte Hypertrophy, Hypoxia, Elevated Fibrosis, and Insulin Resistance in Simian Adipose Tissue and Human Adipocytes.
Ngono Ayissi K, Gorwood J, Le Pelletier L, Bourgeois C, Beaupère C, Auclair M, Foresti R, Motterlini R, Atlan M, Barrail-Tran A, Le Grand R, Desjardins D, Fève B, Lambotte O, Capeau J, Béréziat V, Lagathu C. Ngono Ayissi K, et al. Among authors: le grand r, le pelletier l. Cells. 2022 Jun 4;11(11):1841. doi: 10.3390/cells11111841. Cells. 2022. PMID: 35681536 Free PMC article.
Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection.
Damouche A, Lazure T, Avettand-Fènoël V, Huot N, Dejucq-Rainsford N, Satie AP, Mélard A, David L, Gommet C, Ghosn J, Noel N, Pourcher G, Martinez V, Benoist S, Béréziat V, Cosma A, Favier B, Vaslin B, Rouzioux C, Capeau J, Müller-Trutwin M, Dereuddre-Bosquet N, Le Grand R, Lambotte O, Bourgeois C. Damouche A, et al. Among authors: le grand r. PLoS Pathog. 2015 Sep 24;11(9):e1005153. doi: 10.1371/journal.ppat.1005153. eCollection 2015 Sep. PLoS Pathog. 2015. PMID: 26402858 Free PMC article.
Early SIV and HIV infection promotes the LILRB2/MHC-I inhibitory axis in cDCs.
Alaoui L, Palomino G, Zurawski S, Zurawski G, Coindre S, Dereuddre-Bosquet N, Lecuroux C, Goujard C, Vaslin B, Bourgeois C, Roques P, Le Grand R, Lambotte O, Favier B. Alaoui L, et al. Among authors: le grand r. Cell Mol Life Sci. 2018 May;75(10):1871-1887. doi: 10.1007/s00018-017-2712-9. Epub 2017 Nov 13. Cell Mol Life Sci. 2018. PMID: 29134249 Free PMC article.
Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection.
Echebli N, Tchitchek N, Dupuy S, Bruel T, Peireira Bittencourt Passaes C, Bosquet N, Le Grand R, Bourgeois C, Favier B, Cheynier R, Lambotte O, Vaslin B. Echebli N, et al. Among authors: le grand r. PLoS One. 2018 Jan 11;13(1):e0190334. doi: 10.1371/journal.pone.0190334. eCollection 2018. PLoS One. 2018. PMID: 29324751 Free PMC article.
Mass Cytometry Analysis Reveals the Landscape and Dynamics of CD32a+ CD4+ T Cells From Early HIV Infection to Effective cART.
Coindre S, Tchitchek N, Alaoui L, Vaslin B, Bourgeois C, Goujard C, Avettand-Fenoel V, Lecuroux C, Bruhns P, Le Grand R, Beignon AS, Lambotte O, Favier B; ANRS CO6 PRIMO Cohort. Coindre S, et al. Among authors: le grand r. Front Immunol. 2018 Jun 4;9:1217. doi: 10.3389/fimmu.2018.01217. eCollection 2018. Front Immunol. 2018. PMID: 29915583 Free PMC article.
The Frequencies of Immunosuppressive Cells in Adipose Tissue Differ in Human, Non-human Primate, and Mouse Models.
Laparra A, Tricot S, Le Van M, Damouche A, Gorwood J, Vaslin B, Favier B, Benoist S, Ho Tsong Fang R, Bosquet N, Le Grand R, Chapon C, Lambotte O, Bourgeois C. Laparra A, et al. Among authors: le van m, le grand r. Front Immunol. 2019 Feb 5;10:117. doi: 10.3389/fimmu.2019.00117. eCollection 2019. Front Immunol. 2019. PMID: 30804937 Free PMC article.
FOXO1 transcription factor plays a key role in T cell-HIV-1 interaction.
Roux A, Leroy H, De Muylder B, Bracq L, Oussous S, Dusanter-Fourt I, Chougui G, Tacine R, Randriamampita C, Desjardins D, Le Grand R, Bouillaud F, Benichou S, Margottin-Goguet F, Cheynier R, Bismuth G, Mangeney M. Roux A, et al. Among authors: le grand r. PLoS Pathog. 2019 May 1;15(5):e1007669. doi: 10.1371/journal.ppat.1007669. eCollection 2019 May. PLoS Pathog. 2019. PMID: 31042779 Free PMC article.
345 results