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PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment.
Thumkeo D, Punyawatthananukool S, Prasongtanakij S, Matsuura R, Arima K, Nie H, Yamamoto R, Aoyama N, Hamaguchi H, Sugahara S, Takeda S, Charoensawan V, Tanaka A, Sakaguchi S, Narumiya S. Thumkeo D, et al. Among authors: tanaka a. Cell Rep. 2022 Jun 7;39(10):110914. doi: 10.1016/j.celrep.2022.110914. Cell Rep. 2022. PMID: 35675777 Free article.
Regulatory T cells in cancer immunotherapy.
Tanaka A, Sakaguchi S. Tanaka A, et al. Cell Res. 2017 Jan;27(1):109-118. doi: 10.1038/cr.2016.151. Epub 2016 Dec 20. Cell Res. 2017. PMID: 27995907 Free PMC article. Review.
Targeting Treg cells in cancer immunotherapy.
Tanaka A, Sakaguchi S. Tanaka A, et al. Eur J Immunol. 2019 Aug;49(8):1140-1146. doi: 10.1002/eji.201847659. Epub 2019 Jul 5. Eur J Immunol. 2019. PMID: 31257581 Free article. Review.
Immunology. Early life Aire.
Tanaka A, Sakaguchi S. Tanaka A, et al. Science. 2015 May 1;348(6234):506-7. doi: 10.1126/science.aab2998. Epub 2015 Apr 30. Science. 2015. PMID: 25931543 No abstract available.
Regulatory T Cells and Human Disease.
Sakaguchi S, Mikami N, Wing JB, Tanaka A, Ichiyama K, Ohkura N. Sakaguchi S, et al. Among authors: tanaka a. Annu Rev Immunol. 2020 Apr 26;38:541-566. doi: 10.1146/annurev-immunol-042718-041717. Epub 2020 Feb 4. Annu Rev Immunol. 2020. PMID: 32017635 Review.
CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory.
Kidani Y, Nogami W, Yasumizu Y, Kawashima A, Tanaka A, Sonoda Y, Tona Y, Nashiki K, Matsumoto R, Hagiwara M, Osaki M, Dohi K, Kanazawa T, Ueyama A, Yoshikawa M, Yoshida T, Matsumoto M, Hojo K, Shinonome S, Yoshida H, Hirata M, Haruna M, Nakamura Y, Motooka D, Okuzaki D, Sugiyama Y, Kinoshita M, Okuno T, Kato T, Hatano K, Uemura M, Imamura R, Yokoi K, Tanemura A, Shintani Y, Kimura T, Nonomura N, Wada H, Mori M, Doki Y, Ohkura N, Sakaguchi S. Kidani Y, et al. Among authors: tanaka a. Proc Natl Acad Sci U S A. 2022 Feb 15;119(7):e2114282119. doi: 10.1073/pnas.2114282119. Proc Natl Acad Sci U S A. 2022. PMID: 35140181 Free PMC article.
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody.
Ha D, Tanaka A, Kibayashi T, Tanemura A, Sugiyama D, Wing JB, Lim EL, Teng KWW, Adeegbe D, Newell EW, Katayama I, Nishikawa H, Sakaguchi S. Ha D, et al. Among authors: tanaka a. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):609-618. doi: 10.1073/pnas.1812186116. Epub 2018 Dec 26. Proc Natl Acad Sci U S A. 2019. PMID: 30587582 Free PMC article.
6,210 results