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PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment.
Thumkeo D, Punyawatthananukool S, Prasongtanakij S, Matsuura R, Arima K, Nie H, Yamamoto R, Aoyama N, Hamaguchi H, Sugahara S, Takeda S, Charoensawan V, Tanaka A, Sakaguchi S, Narumiya S. Thumkeo D, et al. Among authors: sakaguchi s. Cell Rep. 2022 Jun 7;39(10):110914. doi: 10.1016/j.celrep.2022.110914. Cell Rep. 2022. PMID: 35675777 Free article.
Regulatory T cells and immune tolerance.
Sakaguchi S, Yamaguchi T, Nomura T, Ono M. Sakaguchi S, et al. Cell. 2008 May 30;133(5):775-87. doi: 10.1016/j.cell.2008.05.009. Cell. 2008. PMID: 18510923 Free article. Review.
T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development.
Ohkura N, Hamaguchi M, Morikawa H, Sugimura K, Tanaka A, Ito Y, Osaki M, Tanaka Y, Yamashita R, Nakano N, Huehn J, Fehling HJ, Sparwasser T, Nakai K, Sakaguchi S. Ohkura N, et al. Among authors: sakaguchi s. Immunity. 2012 Nov 16;37(5):785-99. doi: 10.1016/j.immuni.2012.09.010. Epub 2012 Nov 1. Immunity. 2012. PMID: 23123060 Free article.
Immunology. Early life Aire.
Tanaka A, Sakaguchi S. Tanaka A, et al. Among authors: sakaguchi s. Science. 2015 May 1;348(6234):506-7. doi: 10.1126/science.aab2998. Epub 2015 Apr 30. Science. 2015. PMID: 25931543 No abstract available.
Regulatory T cells in cancer immunotherapy.
Tanaka A, Sakaguchi S. Tanaka A, et al. Among authors: sakaguchi s. Cell Res. 2017 Jan;27(1):109-118. doi: 10.1038/cr.2016.151. Epub 2016 Dec 20. Cell Res. 2017. PMID: 27995907 Free PMC article. Review.
Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells.
Ikeda K, Kinoshita M, Kayama H, Nagamori S, Kongpracha P, Umemoto E, Okumura R, Kurakawa T, Murakami M, Mikami N, Shintani Y, Ueno S, Andou A, Ito M, Tsumura H, Yasutomo K, Ozono K, Takashima S, Sakaguchi S, Kanai Y, Takeda K. Ikeda K, et al. Among authors: sakaguchi s. Cell Rep. 2017 Nov 14;21(7):1824-1838. doi: 10.1016/j.celrep.2017.10.082. Cell Rep. 2017. PMID: 29141216 Free article.
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.
Hirota K, Hashimoto M, Ito Y, Matsuura M, Ito H, Tanaka M, Watanabe H, Kondoh G, Tanaka A, Yasuda K, Kopf M, Potocnik AJ, Stockinger B, Sakaguchi N, Sakaguchi S. Hirota K, et al. Among authors: sakaguchi n, sakaguchi s. Immunity. 2018 Jun 19;48(6):1220-1232.e5. doi: 10.1016/j.immuni.2018.04.009. Epub 2018 May 22. Immunity. 2018. PMID: 29802020 Free PMC article.
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody.
Ha D, Tanaka A, Kibayashi T, Tanemura A, Sugiyama D, Wing JB, Lim EL, Teng KWW, Adeegbe D, Newell EW, Katayama I, Nishikawa H, Sakaguchi S. Ha D, et al. Among authors: sakaguchi s. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):609-618. doi: 10.1073/pnas.1812186116. Epub 2018 Dec 26. Proc Natl Acad Sci U S A. 2019. PMID: 30587582 Free PMC article.
1,198 results