Horenstein N - Search Results

1

Structure-Functional Selectivity Relationship Studies on A-86929 Analogs and Small Aryl Fragments toward the Discovery of Biased Dopamine D1 Receptor Agonists.

Li H, Mirabel R, Zimmerman J, Ghiviriga I, Phidd DK, Horenstein N, Urs NM. Li H, et al. Among authors: horenstein n. ACS Chem Neurosci. 2022 Jun 15;13(12):1818-1831. doi: 10.1021/acschemneuro.2c00235. Epub 2022 Jun 6. ACS Chem Neurosci. 2022. PMID: 35658399

2

Synthesis of saccharin-glycoconjugates targeting carbonic anhydrase using a one-pot cyclization/deprotection strategy.

Murray AB, Quadri M, Li H, McKenna R, Horenstein NA. Murray AB, et al. Carbohydr Res. 2019 Apr 1;476:65-70. doi: 10.1016/j.carres.2019.03.001. Epub 2019 Mar 19. Carbohydr Res. 2019. PMID: 30921738 Free PMC article.

3

Selective Agonists and Antagonists of α9 Versus α7 Nicotinic Acetylcholine Receptors.

Papke RL, Andleeb H, Stokes C, Quadri M, Horenstein NA. Papke RL, et al. Among authors: horenstein na. ACS Chem Neurosci. 2022 Mar 2;13(5):624-637. doi: 10.1021/acschemneuro.1c00747. Epub 2022 Feb 15. ACS Chem Neurosci. 2022. PMID: 35167270 Free PMC article.

4

Computational insights into ligand-induced G protein and β-arrestin signaling of the dopamine D1 receptor.

Li H, Urs NM, Horenstein N. Li H, et al. Among authors: horenstein n. J Comput Aided Mol Des. 2023 Jun;37(5-6):227-244. doi: 10.1007/s10822-023-00503-7. Epub 2023 Apr 15. J Comput Aided Mol Des. 2023. PMID: 37060492

5

Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist.

Papke RL, Schiff HC, Jack BA, Horenstein NA. Papke RL, et al. Neurosci Lett. 2005 Apr 22;378(3):140-4. doi: 10.1016/j.neulet.2004.12.025. Epub 2005 Jan 5. Neurosci Lett. 2005. PMID: 15781147

6

Anti-inflammatory Silent Agonists.

Horenstein NA, Papke RL. Horenstein NA, et al. ACS Med Chem Lett. 2017 Sep 26;8(10):989-991. doi: 10.1021/acsmedchemlett.7b00368. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057037 Free PMC article.

7

Mechanism of Manganese Dysregulation of Dopamine Neuronal Activity.

Lin M, Colon-Perez LM, Sambo DO, Miller DR, Lebowitz JJ, Jimenez-Rondan F, Cousins RJ, Horenstein N, Aydemir TB, Febo M, Khoshbouei H. Lin M, et al. Among authors: horenstein n. J Neurosci. 2020 Jul 22;40(30):5871-5891. doi: 10.1523/JNEUROSCI.2830-19.2020. Epub 2020 Jun 23. J Neurosci. 2020. PMID: 32576620 Free PMC article.

8

Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation.

Pismataro MC, Horenstein NA, Stokes C, Quadri M, De Amici M, Papke RL, Dallanoce C. Pismataro MC, et al. Eur J Med Chem. 2020 Nov 1;205:112669. doi: 10.1016/j.ejmech.2020.112669. Epub 2020 Jul 28. Eur J Med Chem. 2020. PMID: 32810771 Free PMC article.

9

Effects at a distance in alpha 7 nAChR selective agonists: benzylidene substitutions that regulate potency and efficacy.

Papke RL, Meyer EM, Lavieri S, Bollampally SR, Papke TA, Horenstein NA, Itoh Y, Porter Papke JK. Papke RL, et al. Neuropharmacology. 2004 Jun;46(7):1023-38. doi: 10.1016/j.neuropharm.2004.01.005. Neuropharmacology. 2004. PMID: 15081799

10

The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors.

Stokes C, Papke JK, Horenstein NA, Kem WR, McCormack TJ, Papke RL. Stokes C, et al. Mol Pharmacol. 2004 Jul;66(1):14-24. doi: 10.1124/mol.66.1.14. Mol Pharmacol. 2004. PMID: 15213292

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