Ou TM - Search Results

1

A Novel Strategy for Regulating mRNA's Degradation via Interfering the AUF1's Binding to mRNA.

Li KT, Wu XZ, Sun ZY, Ou TM. Li KT, et al. Among authors: ou tm. Molecules. 2022 May 16;27(10):3182. doi: 10.3390/molecules27103182. Molecules. 2022. PMID: 35630659 Free PMC article.

2

Discovery of Small Molecules for Up-Regulating the Translation of Antiamyloidogenic Secretase, a Disintegrin and Metalloproteinase 10 (ADAM10), by Binding to the G-Quadruplex-Forming Sequence in the 5' Untranslated Region (UTR) of Its mRNA.

Dai J, Liu ZQ, Wang XQ, Lin J, Yao PF, Huang SL, Ou TM, Tan JH, Li D, Gu LQ, Huang ZS. Dai J, et al. Among authors: ou tm. J Med Chem. 2015 May 14;58(9):3875-91. doi: 10.1021/acs.jmedchem.5b00139. Epub 2015 Apr 15. J Med Chem. 2015. PMID: 25822852

3

Design, Synthesis, and Evaluation of Novel p-(Methylthio)styryl Substituted Quindoline Derivatives as Neuroblastoma RAS (NRAS) Repressors via Specific Stabilizing the RNA G-Quadruplex.

Peng W, Sun ZY, Zhang Q, Cheng SQ, Wang SK, Wang XN, Kuang GT, Su XX, Tan JH, Huang ZS, Ou TM. Peng W, et al. Among authors: ou tm. J Med Chem. 2018 Aug 9;61(15):6629-6646. doi: 10.1021/acs.jmedchem.8b00257. Epub 2018 Jul 23. J Med Chem. 2018. PMID: 29799749

4

Developing Novel G-Quadruplex Ligands: from Interaction with Nucleic Acids to Interfering with Nucleic Acid⁻Protein Interaction.

Sun ZY, Wang XN, Cheng SQ, Su XX, Ou TM. Sun ZY, et al. Among authors: ou tm. Molecules. 2019 Jan 22;24(3):396. doi: 10.3390/molecules24030396. Molecules. 2019. PMID: 30678288 Free PMC article. Review.

5

MYC modulators in cancer: a patent review.

Wang XN, Su XX, Cheng SQ, Sun ZY, Huang ZS, Ou TM. Wang XN, et al. Among authors: ou tm. Expert Opin Ther Pat. 2019 May;29(5):353-367. doi: 10.1080/13543776.2019.1612878. Epub 2019 May 8. Expert Opin Ther Pat. 2019. PMID: 31068032 Review.

6

Design, synthesis, and evaluation of 9-(pyrimidin-2-yl)-9H-carbazole derivatives disrupting mitochondrial homeostasis in human lung adenocarcinoma.

Su XX, Chen YR, Wu JQ, Wu XZ, Li KT, Wang XN, Sun JW, Wang H, Ou TM. Su XX, et al. Among authors: ou tm. Eur J Med Chem. 2022 Mar 15;232:114200. doi: 10.1016/j.ejmech.2022.114200. Epub 2022 Feb 18. Eur J Med Chem. 2022. PMID: 35219149

7

Therapeutic targeting RORγ with natural product N-hydroxyapiosporamide for small cell lung cancer by reprogramming neuroendocrine fate.

Chen J, Hu Y, Zhang J, Wang Q, Wu X, Huang W, Wang Q, Cai G, Wang H, Ou T, Feng W, Liu P, Liu Y, Wang J, Huang J, Wang J. Chen J, et al. Pharmacol Res. 2022 Apr;178:106160. doi: 10.1016/j.phrs.2022.106160. Epub 2022 Mar 6. Pharmacol Res. 2022. PMID: 35259480

8

Cellular nucleic acid binding protein suppresses tumor cell metastasis and induces tumor cell death by downregulating heterogeneous ribonucleoprotein K in fibrosarcoma cells.

Qiu J, Chen S, Su L, Liu J, Xiao N, Ou TM, Tan JH, Gu LQ, Huang ZS, Li D. Qiu J, et al. Among authors: ou tm. Biochim Biophys Acta. 2014 Jul;1840(7):2244-52. doi: 10.1016/j.bbagen.2014.02.025. Epub 2014 Mar 2. Biochim Biophys Acta. 2014. PMID: 24594223

9

Chemical intervention of the NM23-H2 transcriptional programme on c-MYC via a novel small molecule.

Shan C, Lin J, Hou JQ, Liu HY, Chen SB, Chen AC, Ou TM, Tan JH, Li D, Gu LQ, Huang ZS. Shan C, et al. Among authors: ou tm. Nucleic Acids Res. 2015 Aug 18;43(14):6677-91. doi: 10.1093/nar/gkv641. Epub 2015 Jun 27. Nucleic Acids Res. 2015. PMID: 26117539 Free PMC article.

10

Role of Hairpin-Quadruplex DNA Secondary Structural Conversion in the Promoter of hnRNP K in Gene Transcriptional Regulation.

Qiu J, Liu J, Chen S, Ou TM, Tan JH, Gu LQ, Huang ZS, Li D. Qiu J, et al. Among authors: ou tm. Org Lett. 2015 Sep 18;17(18):4584-7. doi: 10.1021/acs.orglett.5b02310. Epub 2015 Sep 2. Org Lett. 2015. PMID: 26332732

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