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A six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma.
Stratford JK, Bentrem DJ, Anderson JM, Fan C, Volmar KA, Marron JS, Routh ED, Caskey LS, Samuel JC, Der CJ, Thorne LB, Calvo BF, Kim HJ, Talamonti MS, Iacobuzio-Donahue CA, Hollingsworth MA, Perou CM, Yeh JJ. Stratford JK, et al. Among authors: hollingsworth ma. PLoS Med. 2010 Jul 13;7(7):e1000307. doi: 10.1371/journal.pmed.1000307. PLoS Med. 2010. PMID: 20644708 Free PMC article.
Cyclin-dependent kinase 5 is amplified and overexpressed in pancreatic cancer and activated by mutant K-Ras.
Eggers JP, Grandgenett PM, Collisson EC, Lewallen ME, Tremayne J, Singh PK, Swanson BJ, Andersen JM, Caffrey TC, High RR, Ouellette M, Hollingsworth MA. Eggers JP, et al. Among authors: hollingsworth ma. Clin Cancer Res. 2011 Oct 1;17(19):6140-50. doi: 10.1158/1078-0432.CCR-10-2288. Epub 2011 Aug 8. Clin Cancer Res. 2011. PMID: 21825040 Free PMC article.
Pathobiological implications of MUC16 expression in pancreatic cancer.
Haridas D, Chakraborty S, Ponnusamy MP, Lakshmanan I, Rachagani S, Cruz E, Kumar S, Das S, Lele SM, Anderson JM, Wittel UA, Hollingsworth MA, Batra SK. Haridas D, et al. Among authors: hollingsworth ma. PLoS One. 2011;6(10):e26839. doi: 10.1371/journal.pone.0026839. Epub 2011 Oct 31. PLoS One. 2011. PMID: 22066010 Free PMC article.
MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer.
Chaika NV, Gebregiworgis T, Lewallen ME, Purohit V, Radhakrishnan P, Liu X, Zhang B, Mehla K, Brown RB, Caffrey T, Yu F, Johnson KR, Powers R, Hollingsworth MA, Singh PK. Chaika NV, et al. Among authors: hollingsworth ma. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13787-92. doi: 10.1073/pnas.1203339109. Epub 2012 Aug 6. Proc Natl Acad Sci U S A. 2012. PMID: 22869720 Free PMC article.
Targeting the NF-κB and mTOR pathways with a quinoxaline urea analog that inhibits IKKβ for pancreas cancer therapy.
Radhakrishnan P, Bryant VC, Blowers EC, Rajule RN, Gautam N, Anwar MM, Mohr AM, Grandgenett PM, Bunt SK, Arnst JL, Lele SM, Alnouti Y, Hollingsworth MA, Natarajan A. Radhakrishnan P, et al. Among authors: hollingsworth ma. Clin Cancer Res. 2013 Apr 15;19(8):2025-35. doi: 10.1158/1078-0432.CCR-12-2909. Epub 2013 Feb 26. Clin Cancer Res. 2013. PMID: 23444213 Free PMC article.
395 results