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Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells.
Marvin DL, You L, Bornes L, van Dinther M, Peters N, Dang H, Hakuno SK, Hornsveld M, Kranenburg O, van Rheenen J, Rohling JHT, Chien MP, Ten Dijke P, Ritsma L. Marvin DL, et al. Among authors: kranenburg o. Cancers (Basel). 2022 May 19;14(10):2508. doi: 10.3390/cancers14102508. Cancers (Basel). 2022. PMID: 35626109 Free PMC article.
Intravital microscopy through an abdominal imaging window reveals a pre-micrometastasis stage during liver metastasis.
Ritsma L, Steller EJ, Beerling E, Loomans CJ, Zomer A, Gerlach C, Vrisekoop N, Seinstra D, van Gurp L, Schäfer R, Raats DA, de Graaff A, Schumacher TN, de Koning EJ, Rinkes IH, Kranenburg O, van Rheenen J. Ritsma L, et al. Among authors: kranenburg o. Sci Transl Med. 2012 Oct 31;4(158):158ra145. doi: 10.1126/scitranslmed.3004394. Sci Transl Med. 2012. PMID: 23115354
Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability.
Jongen JMJ, van der Waals LM, Trumpi K, Laoukili J, Peters NA, Schenning-van Schelven SJ, Govaert KM, Borel Rinkes IHM, Kranenburg O. Jongen JMJ, et al. Among authors: kranenburg o. Oncotarget. 2017 Sep 21;8(49):86296-86311. doi: 10.18632/oncotarget.21145. eCollection 2017 Oct 17. Oncotarget. 2017. PMID: 29156796 Free PMC article.
Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer.
Sacchetti A, Teeuwssen M, Verhagen M, Joosten R, Xu T, Stabile R, van der Steen B, Watson MM, Gusinac A, Kim WK, Ubink I, Van de Werken HJ, Fumagalli A, Paauwe M, Van Rheenen J, Sansom OJ, Kranenburg O, Fodde R. Sacchetti A, et al. Among authors: kranenburg o. Elife. 2021 May 26;10:e61461. doi: 10.7554/eLife.61461. Elife. 2021. PMID: 34036938 Free PMC article.
Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage.
Heinz MC, Peters NA, Oost KC, Lindeboom RGH, van Voorthuijsen L, Fumagalli A, van der Net MC, de Medeiros G, Hageman JH, Verlaan-Klink I, Borel Rinkes IHM, Liberali P, Gloerich M, van Rheenen J, Vermeulen M, Kranenburg O, Snippert HJG. Heinz MC, et al. Among authors: kranenburg o. Cancer Res. 2022 May 16;82(10):1953-1968. doi: 10.1158/0008-5472.CAN-21-0933. Cancer Res. 2022. PMID: 35570706 Free PMC article.
181 results