Nonaka K - Search Results

1

Numerical and Experimental Investigation of the Hydrodynamics in the Single-Use Bioreactor Mobius^® CellReady 3 L.

Kreitmayer D, Gopireddy SR, Matsuura T, Aki Y, Katayama Y, Sawada T, Kakihara H, Nonaka K, Profitlich T, Urbanetz NA, Gutheil E. Kreitmayer D, et al. Among authors: nonaka k. Bioengineering (Basel). 2022 May 11;9(5):206. doi: 10.3390/bioengineering9050206. Bioengineering (Basel). 2022. PMID: 35621484 Free PMC article.

2

CFD-Based and Experimental Hydrodynamic Characterization of the Single-Use Bioreactor Xcellerex^TM XDR-10.

Kreitmayer D, Gopireddy SR, Matsuura T, Aki Y, Katayama Y, Nakano T, Eguchi T, Kakihara H, Nonaka K, Profitlich T, Urbanetz NA, Gutheil E. Kreitmayer D, et al. Among authors: nonaka k. Bioengineering (Basel). 2022 Jan 8;9(1):22. doi: 10.3390/bioengineering9010022. Bioengineering (Basel). 2022. PMID: 35049731 Free PMC article.

3

4-(2,5-Dimethyl-1H-pyrrol-1-yl)-N-(2,5-dioxopyrrolidin-1-yl) benzamide improves monoclonal antibody production in a Chinese hamster ovary cell culture.

Aki Y, Katsumata Y, Kakihara H, Nonaka K, Fujiwara K. Aki Y, et al. Among authors: nonaka k. PLoS One. 2021 Apr 22;16(4):e0250416. doi: 10.1371/journal.pone.0250416. eCollection 2021. PLoS One. 2021. PMID: 33886677 Free PMC article.

4

Development of a stable antibody production system utilizing an Hspa5 promoter in CHO cells.

Tanemura H, Masuda K, Okumura T, Takagi E, Kajihara D, Kakihara H, Nonaka K, Ushioda R. Tanemura H, et al. Among authors: nonaka k. Sci Rep. 2022 May 24;12(1):7239. doi: 10.1038/s41598-022-11342-1. Sci Rep. 2022. PMID: 35610229 Free PMC article.

5

Novel cell line development strategy for monoclonal antibody manufacturing using translational enhancing technology.

Masuda K, Watanabe K, Ueno T, Nakazawa Y, Tanabe Y, Ushiki-Kaku Y, Ogawa-Goto K, Ehara Y, Saeki H, Okumura T, Nonaka K, Kamihira M. Masuda K, et al. Among authors: nonaka k. J Biosci Bioeng. 2022 Mar;133(3):273-280. doi: 10.1016/j.jbiosc.2021.11.010. Epub 2021 Dec 17. J Biosci Bioeng. 2022. PMID: 34930670

6

Efficient antibody production in the methylotrophic yeast Ogataea minuta by overexpression of chaperones.

Suzuki T, Baba S, Ono M, Nonaka K, Ichikawa K, Yabuta M, Ito R, Chiba Y. Suzuki T, et al. Among authors: nonaka k. J Biosci Bioeng. 2017 Aug;124(2):156-163. doi: 10.1016/j.jbiosc.2017.03.001. Epub 2017 Mar 27. J Biosci Bioeng. 2017. PMID: 28356218

7

Efficient enrichment of high-producing recombinant Chinese hamster ovary cells for monoclonal antibody by flow cytometry.

Okumura T, Masuda K, Watanabe K, Miyadai K, Nonaka K, Yabuta M, Omasa T. Okumura T, et al. Among authors: nonaka k. J Biosci Bioeng. 2015 Sep;120(3):340-6. doi: 10.1016/j.jbiosc.2015.01.007. Epub 2015 Feb 12. J Biosci Bioeng. 2015. PMID: 25683450

8

Cation exchange chromatography performed in overloaded mode is effective in removing viruses during the manufacturing of monoclonal antibodies.

Masuda Y, Tsuda M, Hashikawa-Muto C, Takahashi Y, Nonaka K, Wakamatsu K. Masuda Y, et al. Among authors: nonaka k. Biotechnol Prog. 2019 Sep;35(5):e2858. doi: 10.1002/btpr.2858. Epub 2019 Jun 14. Biotechnol Prog. 2019. PMID: 31148380

9

The prevention of an anomalous chromatographic behavior and the resulting successful removal of viruses from monoclonal antibody with an asymmetric charge distribution by using a membrane adsorber in highly efficient, anion-exchange chromatography in flow-through mode.

Masuda Y, Ogino Y, Yamaichi K, Takahashi Y, Nonaka K, Wakamatsu K. Masuda Y, et al. Among authors: nonaka k. Biotechnol Prog. 2020 May;36(3):e2955. doi: 10.1002/btpr.2955. Epub 2020 Jan 21. Biotechnol Prog. 2020. PMID: 31894893

10

Efficient antibody production upon suppression of O mannosylation in the yeast Ogataea minuta.

Kuroda K, Kobayashi K, Kitagawa Y, Nakagawa T, Tsumura H, Komeda T, Shinmi D, Mori E, Motoki K, Fuju K, Sakai T, Nonaka K, Suzuki T, Ichikawa K, Chiba Y, Jigami Y. Kuroda K, et al. Among authors: nonaka k. Appl Environ Microbiol. 2008 Jan;74(2):446-53. doi: 10.1128/AEM.02106-07. Epub 2007 Nov 26. Appl Environ Microbiol. 2008. PMID: 18039826 Free PMC article.

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