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Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses.
McNaughton AL, Paton RS, Edmans M, Youngs J, Wellens J, Phalora P, Fyfe A, Belij-Rammerstorfer S, Bolton JS, Ball J, Carnell GW, Dejnirattisai W, Dold C, Eyre DW, Hopkins P, Howarth A, Kooblall K, Klim H, Leaver S, Lee LN, López-Camacho C, Lumley SF, Macallan DC, Mentzer AJ, Provine NM, Ratcliff J, Slon-Compos J, Skelly D, Stolle L, Supasa P, Temperton N, Walker C, Wang B, Wyncoll D; Oxford Protective T Cell Immunology for COVID-19 (OPTIC) consortium; Scottish National Blood Transfusion Service (SNBTS) consortium; Simmonds P, Lambe T, Baillie JK, Semple MG, Openshaw PJ; International Severe Acute Respiratory and emerging Infection Consortium Coronavirus Clinical Characterisation Consortium (ISARIC4C) investigators; Obolski U, Turner M, Carroll M, Mongkolsapaya J, Screaton G, Kennedy SH, Jarvis L, Barnes E, Dunachie S, Lourenço J, Matthews PC, Bicanic T, Klenerman P, Gupta S, Thompson CP. McNaughton AL, et al. Among authors: gupta s. JCI Insight. 2022 Jul 8;7(13):e156372. doi: 10.1172/jci.insight.156372. JCI Insight. 2022. PMID: 35608920 Free PMC article.
MANTIS: an R package that simulates multilocus models of pathogen evolution.
Lourenço J, Wikramaratna PS, Gupta S. Lourenço J, et al. Among authors: gupta s. BMC Bioinformatics. 2015 May 28;16:176. doi: 10.1186/s12859-015-0598-9. BMC Bioinformatics. 2015. PMID: 26017358 Free PMC article.
MANTIS can simulate and analyse epidemiological time-series generated under the biological assumptions of the strain theory of host-pathogen systems by Gupta et al. CONCLUSIONS: MANTIS wraps a C/C++ ordinary-differential equations system and Runge-Kutta solver into a set o …
MANTIS can simulate and analyse epidemiological time-series generated under the biological assumptions of the strain theory of host-pathogen …
Challenges in dengue research: A computational perspective.
Lourenço J, Tennant W, Faria NR, Walker A, Gupta S, Recker M. Lourenço J, et al. Among authors: gupta s. Evol Appl. 2017 Nov 5;11(4):516-533. doi: 10.1111/eva.12554. eCollection 2018 Apr. Evol Appl. 2017. PMID: 29636803 Free PMC article. Review.
A naturally protective epitope of limited variability as an influenza vaccine target.
Thompson CP, Lourenço J, Walters AA, Obolski U, Edmans M, Palmer DS, Kooblall K, Carnell GW, O'Connor D, Bowden TA, Pybus OG, Pollard AJ, Temperton NJ, Lambe T, Gilbert SC, Gupta S. Thompson CP, et al. Among authors: gupta s. Nat Commun. 2018 Sep 21;9(1):3859. doi: 10.1038/s41467-018-06228-8. Nat Commun. 2018. PMID: 30242149 Free PMC article.
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