Lauffenburger DA - Search Results

1

Cancer-Associated Fibroblasts and Squamous Epithelial Cells Constitute a Unique Microenvironment in a Mouse Model of Inflammation-Induced Colon Cancer.

Vega PN, Nilsson A, Kumar MP, Niitsu H, Simmons AJ, Ro J, Wang J, Chen Z, Joughin BA, Li W, McKinley ET, Liu Q, Roland JT, Washington MK, Coffey RJ, Lauffenburger DA, Lau KS. Vega PN, et al. Among authors: lauffenburger da. Front Oncol. 2022 May 4;12:878920. doi: 10.3389/fonc.2022.878920. eCollection 2022. Front Oncol. 2022. PMID: 35600339 Free PMC article.

2

An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing glioblastoma cells.

Joughin BA, Naegle KM, Huang PH, Yaffe MB, Lauffenburger DA, White FM. Joughin BA, et al. Among authors: lauffenburger da. Mol Biosyst. 2009 Jan;5(1):59-67. doi: 10.1039/b815075c. Epub 2008 Oct 30. Mol Biosyst. 2009. PMID: 19081932 Free PMC article.

3

PTMScout, a Web resource for analysis of high throughput post-translational proteomics studies.

Naegle KM, Gymrek M, Joughin BA, Wagner JP, Welsch RE, Yaffe MB, Lauffenburger DA, White FM. Naegle KM, et al. Among authors: lauffenburger da. Mol Cell Proteomics. 2010 Nov;9(11):2558-70. doi: 10.1074/mcp.M110.001206. Epub 2010 Jul 14. Mol Cell Proteomics. 2010. PMID: 20631208 Free PMC article.

4

In vivo systems analysis identifies spatial and temporal aspects of the modulation of TNF-α-induced apoptosis and proliferation by MAPKs.

Lau KS, Juchheim AM, Cavaliere KR, Philips SR, Lauffenburger DA, Haigis KM. Lau KS, et al. Among authors: lauffenburger da. Sci Signal. 2011 Mar 22;4(165):ra16. doi: 10.1126/scisignal.2001338. Sci Signal. 2011. PMID: 21427409 Free PMC article.

5

BAY61-3606 affects the viability of colon cancer cells in a genotype-directed manner.

Lau KS, Zhang T, Kendall KR, Lauffenburger D, Gray NS, Haigis KM. Lau KS, et al. PLoS One. 2012;7(7):e41343. doi: 10.1371/journal.pone.0041343. Epub 2012 Jul 18. PLoS One. 2012. PMID: 22815993 Free PMC article.

6

Protein kinases display minimal interpositional dependence on substrate sequence: potential implications for the evolution of signalling networks.

Joughin BA, Liu C, Lauffenburger DA, Hogue CW, Yaffe MB. Joughin BA, et al. Among authors: lauffenburger da. Philos Trans R Soc Lond B Biol Sci. 2012 Sep 19;367(1602):2574-83. doi: 10.1098/rstb.2012.0010. Philos Trans R Soc Lond B Biol Sci. 2012. PMID: 22889908 Free PMC article.

7

Multi-scale in vivo systems analysis reveals the influence of immune cells on TNF-α-induced apoptosis in the intestinal epithelium.

Lau KS, Cortez-Retamozo V, Philips SR, Pittet MJ, Lauffenburger DA, Haigis KM. Lau KS, et al. Among authors: lauffenburger da. PLoS Biol. 2012;10(9):e1001393. doi: 10.1371/journal.pbio.1001393. Epub 2012 Sep 25. PLoS Biol. 2012. PMID: 23055830 Free PMC article.

8

Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice.

Miraldi ER, Sharfi H, Friedline RH, Johnson H, Zhang T, Lau KS, Ko HJ, Curran TG, Haigis KM, Yaffe MB, Bonneau R, Lauffenburger DA, Kahn BB, Kim JK, Neel BG, Saghatelian A, White FM. Miraldi ER, et al. Among authors: lauffenburger da. Integr Biol (Camb). 2013 Jul 24;5(7):940-63. doi: 10.1039/c3ib40013a. Epub 2013 May 20. Integr Biol (Camb). 2013. PMID: 23685806 Free PMC article.

9

Network analysis of differential Ras isoform mutation effects on intestinal epithelial responses to TNF-α.

Lau KS, Schrier SB, Gierut J, Lyons J, Lauffenburger DA, Haigis KM. Lau KS, et al. Among authors: lauffenburger da. Integr Biol (Camb). 2013 Nov;5(11):1355-65. doi: 10.1039/c3ib40062j. Epub 2013 Oct 2. Integr Biol (Camb). 2013. PMID: 24084984 Free PMC article.

10

Tandem phosphorylation within an intrinsically disordered region regulates ACTN4 function.

Travers T, Shao H, Joughin BA, Lauffenburger DA, Wells A, Camacho CJ. Travers T, et al. Among authors: lauffenburger da. Sci Signal. 2015 May 26;8(378):ra51. doi: 10.1126/scisignal.aaa1977. Sci Signal. 2015. PMID: 26012634 Free PMC article.

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