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Ion channel dysfunction in cerebellar ataxia.
Bushart DD, Shakkottai VG. Bushart DD, et al. Among authors: shakkottai vg. Neurosci Lett. 2019 Jan 1;688:41-48. doi: 10.1016/j.neulet.2018.02.005. Epub 2018 Feb 5. Neurosci Lett. 2019. PMID: 29421541 Free PMC article. Review.
Targeting potassium channels to treat cerebellar ataxia.
Bushart DD, Chopra R, Singh V, Murphy GG, Wulff H, Shakkottai VG. Bushart DD, et al. Among authors: shakkottai vg. Ann Clin Transl Neurol. 2018 Jan 22;5(3):297-314. doi: 10.1002/acn3.527. eCollection 2018 Mar. Ann Clin Transl Neurol. 2018. PMID: 29560375 Free PMC article.
Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann-Pick diseases.
Schultz ML, Fawaz MV, Azaria RD, Hollon TC, Liu EA, Kunkel TJ, Halseth TA, Krus KL, Ming R, Morin EE, McLoughlin HS, Bushart DD, Paulson HL, Shakkottai VG, Orringer DA, Schwendeman AS, Lieberman AP. Schultz ML, et al. Among authors: shakkottai vg. BMC Med. 2019 Nov 11;17(1):200. doi: 10.1186/s12916-019-1423-5. BMC Med. 2019. PMID: 31711490 Free PMC article.
Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7.
Stoyas CA, Bushart DD, Switonski PM, Ward JM, Alaghatta A, Tang MB, Niu C, Wadhwa M, Huang H, Savchenko A, Gariani K, Xie F, Delaney JR, Gaasterland T, Auwerx J, Shakkottai VG, La Spada AR. Stoyas CA, et al. Among authors: shakkottai vg. Neuron. 2020 Feb 19;105(4):630-644.e9. doi: 10.1016/j.neuron.2019.11.019. Epub 2019 Dec 16. Neuron. 2020. PMID: 31859031 Free PMC article.
Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1.
Chopra R, Bushart DD, Cooper JP, Yellajoshyula D, Morrison LM, Huang H, Handler HP, Man LJ, Dansithong W, Scoles DR, Pulst SM, Orr HT, Shakkottai VG. Chopra R, et al. Among authors: shakkottai vg. Hum Mol Genet. 2020 Nov 25;29(19):3249-3265. doi: 10.1093/hmg/ddaa212. Hum Mol Genet. 2020. PMID: 32964235 Free PMC article.
86 results