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Delayed fractional dosing with RTS,S/AS01 improves humoral immunity to malaria via a balance of polyfunctional NANP6- and Pf16-specific antibodies.
Das J, Fallon JK, Yu TC, Michell A, Suscovich TJ, Linde C, Natarajan H, Weiner J, Coccia M, Gregory S, Ackerman ME, Bergmann-Leitner E, Fontana L, Dutta S, Lauffenburger DA, Jongert E, Wille-Reece U, Alter G. Das J, et al. Med. 2021 Nov 12;2(11):1269-1286.e9. doi: 10.1016/j.medj.2021.10.003. Med. 2021. PMID: 35590199 Free article. Clinical Trial.
Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination.
Suscovich TJ, Fallon JK, Das J, Demas AR, Crain J, Linde CH, Michell A, Natarajan H, Arevalo C, Broge T, Linnekin T, Kulkarni V, Lu R, Slein MD, Luedemann C, Marquette M, March S, Weiner J, Gregory S, Coccia M, Flores-Garcia Y, Zavala F, Ackerman ME, Bergmann-Leitner E, Hendriks J, Sadoff J, Dutta S, Bhatia SN, Lauffenburger DA, Jongert E, Wille-Reece U, Alter G. Suscovich TJ, et al. Among authors: das j. Sci Transl Med. 2020 Jul 22;12(553):eabb4757. doi: 10.1126/scitranslmed.abb4757. Sci Transl Med. 2020. PMID: 32718991
Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV.
Ackerman ME, Das J, Pittala S, Broge T, Linde C, Suscovich TJ, Brown EP, Bradley T, Natarajan H, Lin S, Sassic JK, O'Keefe S, Mehta N, Goodman D, Sips M, Weiner JA, Tomaras GD, Haynes BF, Lauffenburger DA, Bailey-Kellogg C, Roederer M, Alter G. Ackerman ME, et al. Among authors: das j. Nat Med. 2018 Oct;24(10):1590-1598. doi: 10.1038/s41591-018-0161-0. Epub 2018 Sep 3. Nat Med. 2018. PMID: 30177821 Free PMC article.
Mining for humoral correlates of HIV control and latent reservoir size.
Das J, Devadhasan A, Linde C, Broge T, Sassic J, Mangano M, O'Keefe S, Suscovich T, Streeck H, Irrinki A, Pohlmeyer C, Min-Oo G, Lin S, Weiner JA, Cihlar T, Ackerman ME, Julg B, Deeks S, Lauffenburger DA, Alter G. Das J, et al. PLoS Pathog. 2020 Oct 13;16(10):e1008868. doi: 10.1371/journal.ppat.1008868. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33048992 Free PMC article.
Analysis of Complement-Mediated Lysis of Simian Immunodeficiency Virus (SIV) and SIV-Infected Cells Reveals Sex Differences in Vaccine-Induced Immune Responses in Rhesus Macaques.
Miller-Novak LK, Das J, Musich TA, Demberg T, Weiner JA, Venzon DJ, Mohanram V, Vargas-Inchaustegui DA, Tuero I, Ackerman ME, Alter G, Robert-Guroff M. Miller-Novak LK, et al. Among authors: das j. J Virol. 2018 Sep 12;92(19):e00721-18. doi: 10.1128/JVI.00721-18. Print 2018 Oct 1. J Virol. 2018. PMID: 30021899 Free PMC article.
Upper and lower respiratory tract correlates of protection against respiratory syncytial virus following vaccination of nonhuman primates.
Zohar T, Hsiao JC, Mehta N, Das J, Devadhasan A, Karpinski W, Callahan C, Citron MP, DiStefano DJ, Touch S, Wen Z, Sachs JR, Cejas PJ, Espeseth AS, Lauffenburger DA, Bett AJ, Alter G. Zohar T, et al. Among authors: das j. Cell Host Microbe. 2022 Jan 12;30(1):41-52.e5. doi: 10.1016/j.chom.2021.11.006. Epub 2021 Dec 7. Cell Host Microbe. 2022. PMID: 34879230 Free article.
A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus.
Gunn BM, Yu WH, Karim MM, Brannan JM, Herbert AS, Wec AZ, Halfmann PJ, Fusco ML, Schendel SL, Gangavarapu K, Krause T, Qiu X, He S, Das J, Suscovich TJ, Lai J, Chandran K, Zeitlin L, Crowe JE Jr, Lauffenburger D, Kawaoka Y, Kobinger GP, Andersen KG, Dye JM, Saphire EO, Alter G. Gunn BM, et al. Among authors: das j. Cell Host Microbe. 2018 Aug 8;24(2):221-233.e5. doi: 10.1016/j.chom.2018.07.009. Cell Host Microbe. 2018. PMID: 30092199 Free PMC article.
Fc Glycan-Mediated Regulation of Placental Antibody Transfer.
Jennewein MF, Goldfarb I, Dolatshahi S, Cosgrove C, Noelette FJ, Krykbaeva M, Das J, Sarkar A, Gorman MJ, Fischinger S, Boudreau CM, Brown J, Cooperrider JH, Aneja J, Suscovich TJ, Graham BS, Lauer GM, Goetghebuer T, Marchant A, Lauffenburger D, Kim AY, Riley LE, Alter G. Jennewein MF, et al. Among authors: das j. Cell. 2019 Jun 27;178(1):202-215.e14. doi: 10.1016/j.cell.2019.05.044. Epub 2019 Jun 13. Cell. 2019. PMID: 31204102 Free PMC article.
Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge.
Felber BK, Lu Z, Hu X, Valentin A, Rosati M, Remmel CAL, Weiner JA, Carpenter MC, Faircloth K, Stanfield-Oakley S, Williams WB, Shen X, Tomaras GD, LaBranche CC, Montefiori D, Trinh HV, Rao M, Alam MS, Vandergrift NA, Saunders KO, Wang Y, Rountree W, Das J, Alter G, Reed SG, Aye PP, Schiro F, Pahar B, Dufour JP, Veazey RS, Marx PA, Venzon DJ, Shaw GM, Ferrari G, Ackerman ME, Haynes BF, Pavlakis GN. Felber BK, et al. Among authors: das j. Cell Rep. 2020 May 12;31(6):107624. doi: 10.1016/j.celrep.2020.107624. Cell Rep. 2020. PMID: 32402293 Free PMC article.
1,853 results