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(R)-Ketamine Induces a Greater Increase in Prefrontal 5-HT Release Than (S)-Ketamine and Ketamine Metabolites via an AMPA Receptor-Independent Mechanism.
Ago Y, Tanabe W, Higuchi M, Tsukada S, Tanaka T, Yamaguchi T, Igarashi H, Yokoyama R, Seiriki K, Kasai A, Nakazawa T, Nakagawa S, Hashimoto K, Hashimoto H. Ago Y, et al. Int J Neuropsychopharmacol. 2019 Oct 1;22(10):665-674. doi: 10.1093/ijnp/pyz041. Int J Neuropsychopharmacol. 2019. PMID: 31325908 Free PMC article.
(S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression.
Yokoyama R, Higuchi M, Tanabe W, Tsukada S, Naito M, Yamaguchi T, Chen L, Kasai A, Seiriki K, Nakazawa T, Nakagawa S, Hashimoto K, Hashimoto H, Ago Y. Yokoyama R, et al. Among authors: ago y. Pharmacol Biochem Behav. 2020 Apr;191:172876. doi: 10.1016/j.pbb.2020.172876. Epub 2020 Feb 20. Pharmacol Biochem Behav. 2020. PMID: 32088360
Activation of the VPAC2 Receptor Impairs Axon Outgrowth and Decreases Dendritic Arborization in Mouse Cortical Neurons by a PKA-Dependent Mechanism.
Takeuchi S, Kawanai T, Yamauchi R, Chen L, Miyaoka T, Yamada M, Asano S, Hayata-Takano A, Nakazawa T, Yano K, Horiguchi N, Nakagawa S, Takuma K, Waschek JA, Hashimoto H, Ago Y. Takeuchi S, et al. Among authors: ago y. Front Neurosci. 2020 Jun 4;14:521. doi: 10.3389/fnins.2020.00521. eCollection 2020. Front Neurosci. 2020. PMID: 32581681 Free PMC article.
Generation of KS-133 as a Novel Bicyclic Peptide with a Potent and Selective VIPR2 Antagonist Activity that Counteracts Cognitive Decline in a Mouse Model of Psychiatric Disorders.
Sakamoto K, Chen L, Miyaoka T, Yamada M, Masutani T, Ishimoto K, Hino N, Nakagawa S, Asano S, Ago Y. Sakamoto K, et al. Among authors: ago y. Front Pharmacol. 2021 Nov 4;12:751587. doi: 10.3389/fphar.2021.751587. eCollection 2021. Front Pharmacol. 2021. PMID: 34819858 Free PMC article.
244 results