Hensel N - Search Results

1

Central and peripheral delivered AAV9-SMN are both efficient but target different pathomechanisms in a mouse model of spinal muscular atrophy.

Reilly A, Deguise MO, Beauvais A, Yaworski R, Thebault S, Tessier DR, Tabard-Cossa V, Hensel N, Schneider BL, Kothary R. Reilly A, et al. Among authors: hensel n. Gene Ther. 2022 Sep;29(9):544-554. doi: 10.1038/s41434-022-00338-1. Epub 2022 Apr 25. Gene Ther. 2022. PMID: 35462564

2

Suppression of the necroptotic cell death pathways improves survival in Smn ^2B/- mice.

Chehade L, Deguise MO, De Repentigny Y, Yaworski R, Beauvais A, Gagnon S, Hensel N, Kothary R. Chehade L, et al. Among authors: hensel n. Front Cell Neurosci. 2022 Aug 3;16:972029. doi: 10.3389/fncel.2022.972029. eCollection 2022. Front Cell Neurosci. 2022. PMID: 35990890 Free PMC article.

3

264th ENMC International Workshop: Multi-system involvement in spinal muscular atrophy Hoofddorp, the Netherlands, November 19th - 21st 2021.

Detering NT, Zambon A, Hensel N, Kothary R, Swoboda K, Gillingwater TH, Baranello G; Workshop participants; Industry participants. Detering NT, et al. Among authors: hensel n. Neuromuscul Disord. 2022 Aug;32(8):697-705. doi: 10.1016/j.nmd.2022.06.005. Epub 2022 Jun 17. Neuromuscul Disord. 2022. PMID: 35794048 No abstract available.

4

The phospho-landscape of the survival of motoneuron protein (SMN) protein: relevance for spinal muscular atrophy (SMA).

Detering NT, Schüning T, Hensel N, Claus P. Detering NT, et al. Among authors: hensel n. Cell Mol Life Sci. 2022 Aug 25;79(9):497. doi: 10.1007/s00018-022-04522-9. Cell Mol Life Sci. 2022. PMID: 36006469 Free PMC article. Review.

5

Renal pathology in a mouse model of severe Spinal Muscular Atrophy is associated with downregulation of Glial Cell-Line Derived Neurotrophic Factor (GDNF).

Allardyce H, Kuhn D, Hernandez-Gerez E, Hensel N, Huang YT, Faller K, Gillingwater TH, Quondamatteo F, Claus P, Parson SH. Allardyce H, et al. Among authors: hensel n. Hum Mol Genet. 2020 Aug 11;29(14):2365-2378. doi: 10.1093/hmg/ddaa126. Hum Mol Genet. 2020. PMID: 32588893

6

Impairment of the neurotrophic signaling hub B-Raf contributes to motoneuron degeneration in spinal muscular atrophy.

Hensel N, Cieri F, Santonicola P, Tapken I, Schüning T, Taiana M, Pagliari E, Joseph A, Fischer S, Heidrich N, Brinkmann H, Kubinski S, Bergmann AK, Richter MF, Jung K, Corti S, Di Schiavi E, Claus P. Hensel N, et al. Proc Natl Acad Sci U S A. 2021 May 4;118(18):e2007785118. doi: 10.1073/pnas.2007785118. Proc Natl Acad Sci U S A. 2021. PMID: 33931501 Free PMC article.

7

Altered bone development with impaired cartilage formation precedes neuromuscular symptoms in spinal muscular atrophy.

Hensel N, Brickwedde H, Tsaknakis K, Grages A, Braunschweig L, Lüders KA, Lorenz HM, Lippross S, Walter LM, Tavassol F, Lienenklaus S, Neunaber C, Claus P, Hell AK. Hensel N, et al. Hum Mol Genet. 2020 Sep 29;29(16):2662-2673. doi: 10.1093/hmg/ddaa145. Hum Mol Genet. 2020. PMID: 32644125

8

The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin.

Nölle A, Zeug A, van Bergeijk J, Tönges L, Gerhard R, Brinkmann H, Al Rayes S, Hensel N, Schill Y, Apkhazava D, Jablonka S, O'mer J, Srivastav RK, Baasner A, Lingor P, Wirth B, Ponimaskin E, Niedenthal R, Grothe C, Claus P. Nölle A, et al. Among authors: hensel n. Hum Mol Genet. 2011 Dec 15;20(24):4865-78. doi: 10.1093/hmg/ddr425. Epub 2011 Sep 14. Hum Mol Genet. 2011. PMID: 21920940

9

Metalloprotease-mediated cleavage of PlexinD1 and its sequestration to actin rods in the motoneuron disease spinal muscular atrophy (SMA).

Rademacher S, Verheijen BM, Hensel N, Peters M, Bora G, Brandes G, Vieira de Sá R, Heidrich N, Fischer S, Brinkmann H, van der Pol WL, Wirth B, Pasterkamp RJ, Claus P. Rademacher S, et al. Among authors: hensel n. Hum Mol Genet. 2017 Oct 15;26(20):3946-3959. doi: 10.1093/hmg/ddx282. Hum Mol Genet. 2017. PMID: 29016853

10

Microtubule-associated protein 1B dysregulates microtubule dynamics and neuronal mitochondrial transport in spinal muscular atrophy.

Bora G, Hensel N, Rademacher S, Koyunoğlu D, Sunguroğlu M, Aksu-Mengeş E, Balcı-Hayta B, Claus P, Erdem-Yurter H. Bora G, et al. Among authors: hensel n. Hum Mol Genet. 2021 Feb 25;29(24):3935-3944. doi: 10.1093/hmg/ddaa275. Hum Mol Genet. 2021. PMID: 33410474

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