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Next generation automated traceless cell chromatography platform for GMP-compliant cell isolation and activation.
Radisch S, Poltorak MP, Wagner M, Cletiu V, Radisch C, Treise I, Pann S, Weigt A, Artner S, Dreher S, Fechner F, Borjan B, Fraessle SP, Effenberger M, Benke E, Navratil G, Hentschel N, Busch DH, Schmidt T, Stemberger C, Germeroth L. Radisch S, et al. Among authors: germeroth l. Sci Rep. 2022 Apr 21;12(1):6572. doi: 10.1038/s41598-022-10320-x. Sci Rep. 2022. PMID: 35449227 Free PMC article.
Expamers: a new technology to control T cell activation.
Poltorak MP, Graef P, Tschulik C, Wagner M, Cletiu V, Dreher S, Borjan B, Fraessle SP, Effenberger M, Turk M, Busch DH, Plitzko J, Kugler DG, Ragan S, Schmidt T, Stemberger C, Germeroth L. Poltorak MP, et al. Among authors: germeroth l. Sci Rep. 2020 Oct 20;10(1):17832. doi: 10.1038/s41598-020-74595-8. Sci Rep. 2020. PMID: 33082362 Free PMC article.
Novel serial positive enrichment technology enables clinical multiparameter cell sorting.
Stemberger C, Dreher S, Tschulik C, Piossek C, Bet J, Yamamoto TN, Schiemann M, Neuenhahn M, Martin K, Schlapschy M, Skerra A, Schmidt T, Edinger M, Riddell SR, Germeroth L, Busch DH. Stemberger C, et al. Among authors: germeroth l. PLoS One. 2012;7(4):e35798. doi: 10.1371/journal.pone.0035798. Epub 2012 Apr 24. PLoS One. 2012. PMID: 22545138 Free PMC article.
Clinical-scale isolation of 'minimally manipulated' cytomegalovirus-specific donor lymphocytes for the treatment of refractory cytomegalovirus disease.
Odendahl M, Grigoleit GU, Bönig H, Neuenhahn M, Albrecht J, Anderl F, Germeroth L, Schmitz M, Bornhäuser M, Einsele H, Seifried E, Busch DH, Tonn T. Odendahl M, et al. Among authors: germeroth l. Cytotherapy. 2014 Sep;16(9):1245-56. doi: 10.1016/j.jcyt.2014.05.023. Cytotherapy. 2014. PMID: 25108651 Free article.
The simultaneous isolation of multiple high and low frequent T-cell populations from donor peripheral blood mononuclear cells using the major histocompatibility complex I-Streptamer isolation technology.
Roex MCJ, Hageman L, Heemskerk MT, Veld SAJ, van Liempt E, Kester MGD, Germeroth L, Stemberger C, Falkenburg JHF, Jedema I. Roex MCJ, et al. Among authors: germeroth l. Cytotherapy. 2018 Apr;20(4):543-555. doi: 10.1016/j.jcyt.2018.01.008. Epub 2018 Feb 12. Cytotherapy. 2018. PMID: 29449085
Reversible HLA multimers (Streptamers) for the isolation of human cytotoxic T lymphocytes functionally active against tumor- and virus-derived antigens.
Neudorfer J, Schmidt B, Huster KM, Anderl F, Schiemann M, Holzapfel G, Schmidt T, Germeroth L, Wagner H, Peschel C, Busch DH, Bernhard H. Neudorfer J, et al. Among authors: germeroth l. J Immunol Methods. 2007 Mar 30;320(1-2):119-31. doi: 10.1016/j.jim.2007.01.001. Epub 2007 Jan 31. J Immunol Methods. 2007. PMID: 17306825
Lowest numbers of primary CD8(+) T cells can reconstitute protective immunity upon adoptive immunotherapy.
Stemberger C, Graef P, Odendahl M, Albrecht J, Dössinger G, Anderl F, Buchholz VR, Gasteiger G, Schiemann M, Grigoleit GU, Schuster FR, Borkhardt A, Versluys B, Tonn T, Seifried E, Einsele H, Germeroth L, Busch DH, Neuenhahn M. Stemberger C, et al. Among authors: germeroth l. Blood. 2014 Jul 24;124(4):628-37. doi: 10.1182/blood-2013-12-547349. Epub 2014 May 22. Blood. 2014. PMID: 24855206 Free article.
Generation of high-avidity, WT1-reactive CD8+ cytotoxic T cell clones with anti-leukemic activity by streptamer technology.
Tunger A, Wehner R, von Bonin M, Kühn D, Heidenreich F, Matko S, Nauerth M, Rücker-Braun E, Dietz S, Link CS, Eugster A, Odendahl M, Busch DH, Tonn T, Bonifacio E, Germeroth L, Schetelig J, Bachmann MP, Bornhäuser M, Schmitz M. Tunger A, et al. Among authors: germeroth l. Leuk Lymphoma. 2017 May;58(5):1246-1249. doi: 10.1080/10428194.2016.1233538. Epub 2016 Nov 16. Leuk Lymphoma. 2017. PMID: 27852136 No abstract available.
56 results