Howell PL - Search Results

1

Co-Operative Biofilm Interactions between Aspergillus fumigatus and Pseudomonas aeruginosa through Secreted Galactosaminogalactan Exopolysaccharide.

Ostapska H, Le Mauff F, Gravelat FN, Snarr BD, Bamford NC, Van Loon JC, McKay G, Nguyen D, Howell PL, Sheppard DC. Ostapska H, et al. Among authors: howell pl. J Fungi (Basel). 2022 Mar 24;8(4):336. doi: 10.3390/jof8040336. J Fungi (Basel). 2022. PMID: 35448567 Free PMC article.

2

Modification and periplasmic translocation of the biofilm exopolysaccharide poly-β-1,6-N-acetyl-D-glucosamine.

Little DJ, Li G, Ing C, DiFrancesco BR, Bamford NC, Robinson H, Nitz M, Pomès R, Howell PL. Little DJ, et al. Among authors: howell pl. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11013-8. doi: 10.1073/pnas.1406388111. Epub 2014 Jul 3. Proc Natl Acad Sci U S A. 2014. PMID: 24994902 Free PMC article.

3

Structural basis for the De-N-acetylation of Poly-β-1,6-N-acetyl-D-glucosamine in Gram-positive bacteria.

Little DJ, Bamford NC, Pokrovskaya V, Robinson H, Nitz M, Howell PL. Little DJ, et al. Among authors: howell pl. J Biol Chem. 2014 Dec 26;289(52):35907-17. doi: 10.1074/jbc.M114.611400. Epub 2014 Oct 30. J Biol Chem. 2014. PMID: 25359777 Free PMC article.

4

The protein BpsB is a poly-β-1,6-N-acetyl-D-glucosamine deacetylase required for biofilm formation in Bordetella bronchiseptica.

Little DJ, Milek S, Bamford NC, Ganguly T, DiFrancesco BR, Nitz M, Deora R, Howell PL. Little DJ, et al. Among authors: howell pl. J Biol Chem. 2015 Sep 11;290(37):22827-40. doi: 10.1074/jbc.M115.672469. Epub 2015 Jul 22. J Biol Chem. 2015. PMID: 26203190 Free PMC article.

5

Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus.

Bamford NC, Snarr BD, Gravelat FN, Little DJ, Lee MJ, Zacharias CA, Chabot JC, Geller AM, Baptista SD, Baker P, Robinson H, Howell PL, Sheppard DC. Bamford NC, et al. Among authors: howell pl. J Biol Chem. 2015 Nov 13;290(46):27438-50. doi: 10.1074/jbc.M115.679050. Epub 2015 Sep 4. J Biol Chem. 2015. PMID: 26342082 Free PMC article.

6

Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation.

Lee MJ, Geller AM, Bamford NC, Liu H, Gravelat FN, Snarr BD, Le Mauff F, Chabot J, Ralph B, Ostapska H, Lehoux M, Cerone RP, Baptista SD, Vinogradov E, Stajich JE, Filler SG, Howell PL, Sheppard DC. Lee MJ, et al. Among authors: howell pl. mBio. 2016 Apr 5;7(2):e00252-16. doi: 10.1128/mBio.00252-16. mBio. 2016. PMID: 27048799 Free PMC article.

7

Biofilm Exopolysaccharides of Pathogenic Fungi: Lessons from Bacteria.

Sheppard DC, Howell PL. Sheppard DC, et al. Among authors: howell pl. J Biol Chem. 2016 Jun 10;291(24):12529-12537. doi: 10.1074/jbc.R116.720995. Epub 2016 Apr 21. J Biol Chem. 2016. PMID: 27129222 Free PMC article. Review.

8

Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms.

Baker P, Hill PJ, Snarr BD, Alnabelseya N, Pestrak MJ, Lee MJ, Jennings LK, Tam J, Melnyk RA, Parsek MR, Sheppard DC, Wozniak DJ, Howell PL. Baker P, et al. Among authors: howell pl. Sci Adv. 2016 May 20;2(5):e1501632. doi: 10.1126/sciadv.1501632. eCollection 2016 May. Sci Adv. 2016. PMID: 27386527 Free PMC article.

9

Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity.

Snarr BD, Baker P, Bamford NC, Sato Y, Liu H, Lehoux M, Gravelat FN, Ostapska H, Baistrocchi SR, Cerone RP, Filler EE, Parsek MR, Filler SG, Howell PL, Sheppard DC. Snarr BD, et al. Among authors: howell pl. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7124-7129. doi: 10.1073/pnas.1702798114. Epub 2017 Jun 20. Proc Natl Acad Sci U S A. 2017. PMID: 28634301 Free PMC article.

10

Hoisted by their own petard: do microbial enzymes hold the solution to treating and preventing biofilm infections?

Snarr BD, Howell PL, Sheppard DC. Snarr BD, et al. Among authors: howell pl. Future Microbiol. 2018 Mar;13:395-398. doi: 10.2217/fmb-2017-0243. Epub 2018 Feb 14. Future Microbiol. 2018. PMID: 29441819 No abstract available.

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