Annaert PP - Search Results

1

HIV protease inhibitors Nelfinavir and Lopinavir/Ritonavir markedly improve lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect.

Foo CS, Abdelnabi R, Kaptein SJF, Zhang X, Ter Horst S, Mols R, Delang L, Rocha-Pereira J, Coelmont L, Leyssen P, Dallmeier K, Vergote V, Heylen E, Vangeel L, Chatterjee AK, Annaert PP, Augustijns PF, De Jonghe S, Jochmans D, Gouwy M, Cambier S, Vandooren J, Proost P, van Laer C, Weynand B, Neyts J. Foo CS, et al. Among authors: annaert pp. Antiviral Res. 2022 Jun;202:105311. doi: 10.1016/j.antiviral.2022.105311. Epub 2022 Apr 4. Antiviral Res. 2022. PMID: 35390430 Free PMC article.

2

Transport, uptake, and metabolism of the bis(pivaloyloxymethyl)-ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine in an in vitro cell culture system of the intestinal mucosa (Caco-2).

Annaert P, Kinget R, Naesens L, de Clercq E, Augustijns P. Annaert P, et al. Pharm Res. 1997 Apr;14(4):492-6. doi: 10.1023/a:1012155717819. Pharm Res. 1997. PMID: 9144737

3

Antiretroviral efficacy and pharmacokinetics of oral bis(isopropyloxycarbonyloxymethyl)-9-(2-phosphonylmethoxypropyl)adenine in mice.

Naesens L, Bischofberger N, Augustijns P, Annaert P, Van den Mooter G, Arimilli MN, Kim CU, De Clercq E. Naesens L, et al. Antimicrob Agents Chemother. 1998 Jul;42(7):1568-73. doi: 10.1128/AAC.42.7.1568. Antimicrob Agents Chemother. 1998. PMID: 9660984 Free PMC article.

4

In vitro, ex vivo, and in situ intestinal absorption characteristics of the antiviral ester prodrug adefovir dipivoxil.

Annaert P, Tukker JJ, van Gelder J, Naesens L, de Clercq E, van Den Mooter G, Kinget R, Augustijns P. Annaert P, et al. J Pharm Sci. 2000 Aug;89(8):1054-62. doi: 10.1002/1520-6017(200008)89:8<1054::aid-jps10>3.0.co;2-5. J Pharm Sci. 2000. PMID: 10906729

5

Increasing the oral bioavailability of the poorly water soluble drug itraconazole with ordered mesoporous silica.

Mellaerts R, Mols R, Jammaer JA, Aerts CA, Annaert P, Van Humbeeck J, Van den Mooter G, Augustijns P, Martens JA. Mellaerts R, et al. Eur J Pharm Biopharm. 2008 May;69(1):223-30. doi: 10.1016/j.ejpb.2007.11.006. Epub 2007 Nov 23. Eur J Pharm Biopharm. 2008. PMID: 18164930

6

Ordered mesoporous silica induces pH-independent supersaturation of the basic low solubility compound itraconazole resulting in enhanced transepithelial transport.

Mellaerts R, Mols R, Kayaert P, Annaert P, Van Humbeeck J, Van den Mooter G, Martens JA, Augustijns P. Mellaerts R, et al. Int J Pharm. 2008 Jun 5;357(1-2):169-79. doi: 10.1016/j.ijpharm.2008.01.049. Epub 2008 Feb 3. Int J Pharm. 2008. PMID: 18325700

7

Cellular accumulation of cholyl-glycylamido-fluorescein in sandwich-cultured rat hepatocytes: kinetic characterization, transport mechanisms, and effect of human immunodeficiency virus protease inhibitors.

Ye ZW, Augustijns P, Annaert P. Ye ZW, et al. Drug Metab Dispos. 2008 Jul;36(7):1315-21. doi: 10.1124/dmd.107.019398. Epub 2008 Apr 17. Drug Metab Dispos. 2008. PMID: 18420783

8

Intestinal perfusion with mesenteric blood sampling in wild-type and knockout mice: evaluation of a novel tool in biopharmaceutical drug profiling.

Mols R, Brouwers J, Schinkel AH, Annaert P, Augustijns P. Mols R, et al. Drug Metab Dispos. 2009 Jun;37(6):1334-7. doi: 10.1124/dmd.109.026591. Epub 2009 Mar 9. Drug Metab Dispos. 2009. PMID: 19273528

9

Species-specific interaction of HIV protease inhibitors with accumulation of cholyl-glycylamido-fluorescein (CGamF) in sandwich-cultured hepatocytes.

Ye ZW, Van Pelt J, Camus S, Snoeys J, Augustijns P, Annaert P. Ye ZW, et al. J Pharm Sci. 2010 Jun;99(6):2886-98. doi: 10.1002/jps.22018. J Pharm Sci. 2010. PMID: 20014428

10

Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1.

Annaert P, Ye ZW, Stieger B, Augustijns P. Annaert P, et al. Xenobiotica. 2010 Mar;40(3):163-76. doi: 10.3109/00498250903509375. Xenobiotica. 2010. PMID: 20102298 Free article.

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